AF-2112

Cat. No.: HY-155310: FAQs
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AF-2112 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2.

For research use only. We do not sell to patients.

AF-2112 Chemical Structure

CAS No. : 2996821-62-4

Size	Price	Stock
5 mg	USD 210	Ask For Quote & Lead Time
10 mg	USD 340	Ask For Quote & Lead Time
25 mg	USD 680	Ask For Quote & Lead Time
50 mg	USD 1100	Ask For Quote & Lead Time
100 mg	USD 1780	Ask For Quote & Lead Time

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Description	AF-2112 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2.
Molecular Weight	351.37
Formula	C₂₁H₁₈FNO₃
CAS No.	2996821-62-4
SMILES	OC(C1=CC=C(F)C=C1NC2=CC(OCCC3=CC=CC=C3)=CC=C2)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Ahmed Fnaiche, et al. Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Bioorg Med Chem Lett. 2023 Oct 15:95:129488. [Content Brief]

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AF-21122996821-62-4AF2112AF 2112YAPYes-associated proteinTEAD inhibitorCTGFCyr61AxlNF2Inhibitorinhibitorinhibit

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AF-2112

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