2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. AP30663

AP30663 is a KCa2 channel inhibitor that can be used for the study of atrial fibrillation.

For research use only. We do not sell to patients.

AP30663 Chemical Structure

AP30663 Chemical Structure

Size Price Stock Quantity
5 mg USD 230 In-stock
10 mg USD 375 In-stock
25 mg USD 750 In-stock
50 mg USD 1200 In-stock
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200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

AP30663 is a KCa2 channel inhibitor that can be used for the study of atrial fibrillation[1].

Molecular Weight

401.39

Formula

C20H18F3N5O
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(CC#N)C)C[C@@H](NC1=NC2=CC=CC=C2N1)C3=CC=CC(C(F)(F)F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (249.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4913 mL 12.4567 mL 24.9134 mL
5 mM 0.4983 mL 2.4913 mL 4.9827 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.95%

SDS (251 KB)

COA (250 KB) HNMR (351 KB) RP-HPLC (269 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4913 mL 12.4567 mL 24.9134 mL 62.2836 mL
5 mM 0.4983 mL 2.4913 mL 4.9827 mL 12.4567 mL
10 mM 0.2491 mL 1.2457 mL 2.4913 mL 6.2284 mL
15 mM 0.1661 mL 0.8304 mL 1.6609 mL 4.1522 mL
20 mM 0.1246 mL 0.6228 mL 1.2457 mL 3.1142 mL
25 mM 0.0997 mL 0.4983 mL 0.9965 mL 2.4913 mL
30 mM 0.0830 mL 0.4152 mL 0.8304 mL 2.0761 mL
40 mM 0.0623 mL 0.3114 mL 0.6228 mL 1.5571 mL
50 mM 0.0498 mL 0.2491 mL 0.4983 mL 1.2457 mL
60 mM 0.0415 mL 0.2076 mL 0.4152 mL 1.0381 mL
80 mM 0.0311 mL 0.1557 mL 0.3114 mL 0.7785 mL
100 mM 0.0249 mL 0.1246 mL 0.2491 mL 0.6228 mL
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AP30663 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AP30663AP 30663AP-30663Potassium ChannelKcsAatrial fibrillationInhibitorinhibitorinhibit

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