2. Antibody-drug Conjugate/ADC Related
  3. ADC Cytotoxin
  4. AXC-666

AXC-666, an immune agonist, is a Imiquimod (HY-B0180) derivative. AXC-666 can be used for the synthesis of antibody-drug conjugate (ADC).

For research use only. We do not sell to patients.

AXC-666 Chemical Structure

AXC-666 Chemical Structure

CAS No. : 313350-30-0

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5 mg USD 80 In-stock
10 mg USD 130 In-stock
25 mg USD 260 In-stock
50 mg USD 420 In-stock
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Based on 1 publication(s) in Google Scholar

AXC-666 Related Antibodies

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Description

AXC-666, an immune agonist, is a Imiquimod (HY-B0180) derivative. AXC-666 can be used for the synthesis of antibody-drug conjugate (ADC)[1].

Molecular Weight

283.37

Formula

C16H21N5
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

NCCCCN1C(CC)=NC2=C1C3=CC=CC=C3N=C2N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (176.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5290 mL 17.6448 mL 35.2896 mL
5 mM 0.7058 mL 3.5290 mL 7.0579 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5290 mL 17.6448 mL 35.2896 mL 88.2239 mL
5 mM 0.7058 mL 3.5290 mL 7.0579 mL 17.6448 mL
10 mM 0.3529 mL 1.7645 mL 3.5290 mL 8.8224 mL
15 mM 0.2353 mL 1.1763 mL 2.3526 mL 5.8816 mL
20 mM 0.1764 mL 0.8822 mL 1.7645 mL 4.4112 mL
25 mM 0.1412 mL 0.7058 mL 1.4116 mL 3.5290 mL
30 mM 0.1176 mL 0.5882 mL 1.1763 mL 2.9408 mL
40 mM 0.0882 mL 0.4411 mL 0.8822 mL 2.2056 mL
50 mM 0.0706 mL 0.3529 mL 0.7058 mL 1.7645 mL
60 mM 0.0588 mL 0.2941 mL 0.5882 mL 1.4704 mL
80 mM 0.0441 mL 0.2206 mL 0.4411 mL 1.1028 mL
100 mM 0.0353 mL 0.1764 mL 0.3529 mL 0.8822 mL
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AXC-666 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AXC-666313350-30-0AXC666AXC 666ADC CytotoxinADC PayloadInhibitorinhibitorinhibit

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