2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. Benzenesulphonamide

Benzenesulphonamide (compound 1) is a potent carbonic anhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity.

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Benzenesulphonamide Chemical Structure

Benzenesulphonamide Chemical Structure

CAS No. : 98-10-2

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Based on 1 publication(s) in Google Scholar

Benzenesulphonamide Related Antibodies

Top Publications Citing Use of Products

View All Carbonic Anhydrase Isoform Specific Products:

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CA CA I CA Ⅱ CA Ⅸ CA XII

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Description

Benzenesulphonamide (compound 1) is a potent carbonic anhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity[1].

IC50 & Target

CA Ⅱ

 

Molecular Weight

157.19

Formula

C6H7NO2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=CC=C1)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (636.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.3617 mL 31.8086 mL 63.6173 mL
5 mM 1.2723 mL 6.3617 mL 12.7235 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.51%

COA (252 KB) HNMR (125 KB) RP-HPLC (180 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.3617 mL 31.8086 mL 63.6173 mL 159.0432 mL
5 mM 1.2723 mL 6.3617 mL 12.7235 mL 31.8086 mL
10 mM 0.6362 mL 3.1809 mL 6.3617 mL 15.9043 mL
15 mM 0.4241 mL 2.1206 mL 4.2412 mL 10.6029 mL
20 mM 0.3181 mL 1.5904 mL 3.1809 mL 7.9522 mL
25 mM 0.2545 mL 1.2723 mL 2.5447 mL 6.3617 mL
30 mM 0.2121 mL 1.0603 mL 2.1206 mL 5.3014 mL
40 mM 0.1590 mL 0.7952 mL 1.5904 mL 3.9761 mL
50 mM 0.1272 mL 0.6362 mL 1.2723 mL 3.1809 mL
60 mM 0.1060 mL 0.5301 mL 1.0603 mL 2.6507 mL
80 mM 0.0795 mL 0.3976 mL 0.7952 mL 1.9880 mL
100 mM 0.0636 mL 0.3181 mL 0.6362 mL 1.5904 mL
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Benzenesulphonamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Benzenesulphonamide98-10-2Carbonic AnhydraseCarbonate dehydratasecarbonic anhydrasesglaucomaanticancerQSAR studyInhibitorinhibitorinhibit

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