2. Epigenetics
  3. Epigenetic Reader Domain
  4. BET-IN-21

BET-IN-21 (compound 16) is a blood-brain barrier-permeable extra terminal domain (BET) inhibitor with the Ki of 230 nM. BET-IN-21 inhibits microglia activation and has ameliorative effects on experimental autoimmune encephalomyelitis mice.

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BET-IN-21 Chemical Structure

BET-IN-21 Chemical Structure

CAS No. : 3014815-06-3

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BET-IN-21 Related Antibodies

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Description

BET-IN-21 (compound 16) is a blood-brain barrier-permeable extra terminal domain (BET) inhibitor with the Ki of 230 nM. BET-IN-21 inhibits microglia activation and has ameliorative effects on experimental autoimmune encephalomyelitis mice[1].

Molecular Weight

344.41

Formula

C20H20N6
CAS No.
SMILES

CC1=NN(C(C)=C1C2=CC(C3=C4NC=NC4=NC=C3)=CN=C2)CC5CC5
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Purity & Documentation
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BET-IN-21 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BET-IN-213014815-06-3Epigenetic Reader DomainMicrogliaMultiple sclerosisexperimental autoimmune encephalomyelitis miceInhibitorinhibitorinhibit

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BET-IN-21
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HY-157430
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