2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Boc-Val-Ala-PAB

Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs).

For research use only. We do not sell to patients.

Boc-Val-Ala-PAB Chemical Structure

Boc-Val-Ala-PAB Chemical Structure

CAS No. : 1884577-99-4

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Based on 1 publication(s) in Google Scholar

Boc-Val-Ala-PAB Related Antibodies

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Description

Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].

Molecular Weight

393.48

Formula

C20H31N3O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N[C@@H](C)C(NC(C=C1)=CC=C1CO)=O)[C@H](C(C)C)NC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98.24%

COA (246 KB) HNMR (135 KB) RP-HPLC (254 KB)

Handling Instructions (2659 KB)
References
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Boc-Val-Ala-PAB Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Val-Ala-PAB1884577-99-4ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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