2. Protein Tyrosine Kinase/RTK
  3. Btk
  4. Catadegbrutinib

Catadegbrutinib  (Synonyms: BTK-IN-29)

Cat. No.: HY-160141 Purity: 97.79%
SDS
COA
Handling Instructions Technical Support

Catadegbrutinib (BTK-IN-29) (compound 14) is an inhibitor of Btk.

For research use only. We do not sell to patients.

Catadegbrutinib Chemical Structure

Catadegbrutinib Chemical Structure

CAS No. : 2736508-60-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg In-stock
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Based on 1 publication(s) in Google Scholar

Catadegbrutinib Related Antibodies

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Description

Catadegbrutinib (BTK-IN-29) (compound 14) is an inhibitor of Btk[1].

Molecular Weight

851.01

Formula

C47H54N12O4
CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

CC1=C([C@@H](C)NC(C2=NC(C(C)(C)C)=NO2)=O)C=CC(C3=C4C(NC(C5=CN=C(N6CCN(CC6)CC7CCN(C8=CC=C(N9C(NC(CC9)=O)=O)C=C8)CC7)C=C5)=C4)=NC=N3)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (146.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1751 mL 5.8754 mL 11.7507 mL
5 mM 0.2350 mL 1.1751 mL 2.3501 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.79%

SDS (252 KB)

COA (250 KB) HNMR (334 KB) LCMS (86 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1751 mL 5.8754 mL 11.7507 mL 29.3769 mL
5 mM 0.2350 mL 1.1751 mL 2.3501 mL 5.8754 mL
10 mM 0.1175 mL 0.5875 mL 1.1751 mL 2.9377 mL
15 mM 0.0783 mL 0.3917 mL 0.7834 mL 1.9585 mL
20 mM 0.0588 mL 0.2938 mL 0.5875 mL 1.4688 mL
25 mM 0.0470 mL 0.2350 mL 0.4700 mL 1.1751 mL
30 mM 0.0392 mL 0.1958 mL 0.3917 mL 0.9792 mL
40 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.7344 mL
50 mM 0.0235 mL 0.1175 mL 0.2350 mL 0.5875 mL
60 mM 0.0196 mL 0.0979 mL 0.1958 mL 0.4896 mL
80 mM 0.0147 mL 0.0734 mL 0.1469 mL 0.3672 mL
100 mM 0.0118 mL 0.0588 mL 0.1175 mL 0.2938 mL
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Catadegbrutinib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Catadegbrutinib2736508-60-2BTK-IN-29BtkBruton tyrosine kinasebruton's tyrosine kinaseInhibitorinhibitorinhibit

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