2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Bz-Ala-Arg TFA

Bz-Ala-Arg TFA is a dipeptide. Bz-Ala-Arg TFA is also a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) of human pancreatic carboxypeptidase B and plasma carboxypeptidase N. Bz-Ala-Arg TFA can be used to screen competitive inhibitors of these two enzymes.

For research use only. We do not sell to patients.

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Bz-Ala-Arg TFA Chemical Structure

Bz-Ala-Arg TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Bz-Ala-Arg TFA:

Bz-Ala-Arg TFA Related Antibodies

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Description

Bz-Ala-Arg TFA is a dipeptide. Bz-Ala-Arg TFA is also a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) of human pancreatic carboxypeptidase B and plasma carboxypeptidase N. Bz-Ala-Arg TFA can be used to screen competitive inhibitors of these two enzymes[1].

Molecular Weight

463.41

Formula

C18H24F3N5O6
Appearance

Solid

Color

White to off-white

Sequence

{Bz}-Ala-Arg
Sequence Shortening

{Bz}-AR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (215.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1579 mL 10.7896 mL 21.5792 mL
5 mM 0.4316 mL 2.1579 mL 4.3158 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1579 mL 10.7896 mL 21.5792 mL 53.9479 mL
5 mM 0.4316 mL 2.1579 mL 4.3158 mL 10.7896 mL
10 mM 0.2158 mL 1.0790 mL 2.1579 mL 5.3948 mL
15 mM 0.1439 mL 0.7193 mL 1.4386 mL 3.5965 mL
20 mM 0.1079 mL 0.5395 mL 1.0790 mL 2.6974 mL
25 mM 0.0863 mL 0.4316 mL 0.8632 mL 2.1579 mL
30 mM 0.0719 mL 0.3597 mL 0.7193 mL 1.7983 mL
40 mM 0.0539 mL 0.2697 mL 0.5395 mL 1.3487 mL
50 mM 0.0432 mL 0.2158 mL 0.4316 mL 1.0790 mL
60 mM 0.0360 mL 0.1798 mL 0.3597 mL 0.8991 mL
80 mM 0.0270 mL 0.1349 mL 0.2697 mL 0.6743 mL
100 mM 0.0216 mL 0.1079 mL 0.2158 mL 0.5395 mL
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Bz-Ala-Arg TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bz-Ala-ArgEndogenous Metabolitespectrophotometric substratehuman pancreatic carboxypeptidase Bplasma carboxypeptidase NInhibitorinhibitorinhibit

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