Bz-rA (Synonyms: N6-Benzoyladenosine)

Cat. No.: HY-W008388 Purity: 99.51%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Bz-rA (N6-Benzoyladenosine) is a N6-protected adenosine that can be used to synthesize oligoribonucleotides.

For research use only. We do not sell to patients.

Bz-rA Chemical Structure

CAS No. : 4546-55-8

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 28	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 28	In-stock	Estimated Time of Arrival: December 31
Solid
25 g	USD 26	In-stock	Estimated Time of Arrival: December 31
50 g	USD 47	In-stock	Estimated Time of Arrival: December 31
100 g	USD 85	In-stock	Estimated Time of Arrival: December 31
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Biological Activity
Purity & Documentation
References
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Description

Bz-rA (N6-Benzoyladenosine) is a N6-protected adenosine that can be used to synthesize oligoribonucleotides^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
RD	EC₅₀	12 μM Compound: 25	Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay Antiviral activity against Enterovirus 71 infected in human RD cells assessed as cell viability after 3 days by MTS assay	[PMID: 26854380]

Molecular Weight

371.35

Formula

C₁₇H₁₇N₅O₅

CAS No.

4546-55-8

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (269.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6929 mL	13.4644 mL	26.9288 mL
5 mM	0.5386 mL	2.6929 mL	5.3858 mL
10 mM	0.2693 mL	1.3464 mL	2.6929 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (272 KB) SDS (392 KB)

COA (252 KB) HNMR (134 KB) RP-HPLC (229 KB)

Handling Instructions (2659 KB)

References

[1]. Dieter Flockerzi, et al. Nucleoside, XXXVII. Synthese und Eigenschaften von 2′-O- und 3′-O-(tert-Butyldi-methylsilyl)-5′-O-(4-methoxytrityl)- sowie 2′,3′-Bis-O-(tert-butyl-dimethylsilyl)ribonucleosiden — Ausgangssubstanzen für Oligoribonucleotid-Synthesen. Liebigs Annalen der Chemie. 1981, 9 (21): 1568-1585.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.6929 mL	13.4644 mL	26.9288 mL	67.3219 mL
	5 mM	0.5386 mL	2.6929 mL	5.3858 mL	13.4644 mL
	10 mM	0.2693 mL	1.3464 mL	2.6929 mL	6.7322 mL
	15 mM	0.1795 mL	0.8976 mL	1.7953 mL	4.4881 mL
	20 mM	0.1346 mL	0.6732 mL	1.3464 mL	3.3661 mL
	25 mM	0.1077 mL	0.5386 mL	1.0772 mL	2.6929 mL
	30 mM	0.0898 mL	0.4488 mL	0.8976 mL	2.2441 mL
	40 mM	0.0673 mL	0.3366 mL	0.6732 mL	1.6830 mL
	50 mM	0.0539 mL	0.2693 mL	0.5386 mL	1.3464 mL
	60 mM	0.0449 mL	0.2244 mL	0.4488 mL	1.1220 mL
	80 mM	0.0337 mL	0.1683 mL	0.3366 mL	0.8415 mL
	100 mM	0.0269 mL	0.1346 mL	0.2693 mL	0.6732 mL

Bz-rA Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bz-rA4546-55-8N6-BenzoyladenosineNucleoside Antimetabolite/AnalogadenosineoligoribonucleotideInhibitorinhibitorinhibit

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