2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK5-IN-1

CDK5-IN-1, a potent CDK5 inhibitor, is against CDK5 activity less than 10 nM. CDK5-IN-1 is used for kidney diseases research.

For research use only. We do not sell to patients.

CDK5-IN-1 Chemical Structure

CDK5-IN-1 Chemical Structure

CAS No. : 2639540-19-3

Size Price Stock Quantity
5 mg USD 568 In-stock
10 mg USD 910 In-stock
25 mg USD 1815 In-stock
50 mg USD 2900 In-stock
100 mg USD 4650 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

CDK5-IN-1 Related Antibodies

Top Publications Citing Use of Products

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Description

CDK5-IN-1, a potent CDK5 inhibitor, is against CDK5 activity less than 10 nM. CDK5-IN-1 is used for kidney diseases research[1].

IC50 & Target[1]

CDK5

 

Molecular Weight

496.56

Formula

C24H25FN6O3S
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=S(C1=CC=C2C=NC(NC3=CC=C(N4N=C(CO)C=C4)C=C3F)=CC2=N1)(C5CCN(CC5)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (503.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0139 mL 10.0693 mL 20.1386 mL
5 mM 0.4028 mL 2.0139 mL 4.0277 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0139 mL 10.0693 mL 20.1386 mL 50.3464 mL
5 mM 0.4028 mL 2.0139 mL 4.0277 mL 10.0693 mL
10 mM 0.2014 mL 1.0069 mL 2.0139 mL 5.0346 mL
15 mM 0.1343 mL 0.6713 mL 1.3426 mL 3.3564 mL
20 mM 0.1007 mL 0.5035 mL 1.0069 mL 2.5173 mL
25 mM 0.0806 mL 0.4028 mL 0.8055 mL 2.0139 mL
30 mM 0.0671 mL 0.3356 mL 0.6713 mL 1.6782 mL
40 mM 0.0503 mL 0.2517 mL 0.5035 mL 1.2587 mL
50 mM 0.0403 mL 0.2014 mL 0.4028 mL 1.0069 mL
60 mM 0.0336 mL 0.1678 mL 0.3356 mL 0.8391 mL
80 mM 0.0252 mL 0.1259 mL 0.2517 mL 0.6293 mL
100 mM 0.0201 mL 0.1007 mL 0.2014 mL 0.5035 mL
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CDK5-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK5-IN-12639540-19-3CDKCyclin dependent kinasekidney failurekidney stonespolycystic kidney diseaseInhibitorinhibitorinhibit

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