1. Cell Cycle/DNA Damage Anti-infection
  2. CDK HIV
  3. CDK9-IN-30

CDK9-IN-30 is a CDK9 inhibitor that inhibits HIV-1 viral replication.

For research use only. We do not sell to patients.

CDK9-IN-30 Chemical Structure

CDK9-IN-30 Chemical Structure

CAS No. : 748146-89-6

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5 mg USD 150 In-stock
10 mg USD 240 In-stock
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Description

CDK9-IN-30 is a CDK9 inhibitor that inhibits HIV-1 viral replication[1].

IC50 & Target

CDK9, HIV-1[1]

Molecular Weight

293.33

Formula

C16H20FNO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC1(CCCCC1)CC(NC2=CC=C(C=C2)F)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 59 mg/mL (201.14 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4091 mL 17.0456 mL 34.0913 mL
5 mM 0.6818 mL 3.4091 mL 6.8183 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4091 mL 17.0456 mL 34.0913 mL 85.2282 mL
5 mM 0.6818 mL 3.4091 mL 6.8183 mL 17.0456 mL
10 mM 0.3409 mL 1.7046 mL 3.4091 mL 8.5228 mL
15 mM 0.2273 mL 1.1364 mL 2.2728 mL 5.6819 mL
20 mM 0.1705 mL 0.8523 mL 1.7046 mL 4.2614 mL
25 mM 0.1364 mL 0.6818 mL 1.3637 mL 3.4091 mL
30 mM 0.1136 mL 0.5682 mL 1.1364 mL 2.8409 mL
40 mM 0.0852 mL 0.4261 mL 0.8523 mL 2.1307 mL
50 mM 0.0682 mL 0.3409 mL 0.6818 mL 1.7046 mL
60 mM 0.0568 mL 0.2841 mL 0.5682 mL 1.4205 mL
80 mM 0.0426 mL 0.2131 mL 0.4261 mL 1.0654 mL
100 mM 0.0341 mL 0.1705 mL 0.3409 mL 0.8523 mL
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CDK9-IN-30 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CDK9-IN-30
Cat. No.:
HY-147131
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