2. Membrane Transporter/Ion Channel Autophagy
  3. CFTR Autophagy
  4. CFTR corrector 2

CFTR corrector 2 is a cystic fibrosis transmembrane conductance corrector (CFTR), extracted from patent US20140274933.

For research use only. We do not sell to patients.

CFTR corrector 2 Chemical Structure

CFTR corrector 2 Chemical Structure

CAS No. : 1628416-28-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 80 In-stock
Solution
10 mM * 1 mL in DMSO USD 80 In-stock
Solid
1 mg USD 40 In-stock
5 mg USD 75 In-stock
10 mg USD 120 In-stock
25 mg USD 190 In-stock
50 mg USD 350 In-stock
100 mg USD 550 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

CFTR corrector 2 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE CFTR corrector 2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

CFTR corrector 2 is a cystic fibrosis transmembrane conductance corrector (CFTR), extracted from patent US20140274933[1].

IC50 & Target

CFTR[1].
Molecular Weight

486.49

Formula

C27H23FN4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C)C1=CC=C2N=C(C)OC2=C1)CN(N=C(C3=CC=CC(F)=C3)C4=C5C=C(OCC)C=C4)C5=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (128.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0555 mL 10.2777 mL 20.5554 mL
5 mM 0.4111 mL 2.0555 mL 4.1111 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0555 mL 10.2777 mL 20.5554 mL 51.3885 mL
5 mM 0.4111 mL 2.0555 mL 4.1111 mL 10.2777 mL
10 mM 0.2056 mL 1.0278 mL 2.0555 mL 5.1389 mL
15 mM 0.1370 mL 0.6852 mL 1.3704 mL 3.4259 mL
20 mM 0.1028 mL 0.5139 mL 1.0278 mL 2.5694 mL
25 mM 0.0822 mL 0.4111 mL 0.8222 mL 2.0555 mL
30 mM 0.0685 mL 0.3426 mL 0.6852 mL 1.7130 mL
40 mM 0.0514 mL 0.2569 mL 0.5139 mL 1.2847 mL
50 mM 0.0411 mL 0.2056 mL 0.4111 mL 1.0278 mL
60 mM 0.0343 mL 0.1713 mL 0.3426 mL 0.8565 mL
80 mM 0.0257 mL 0.1285 mL 0.2569 mL 0.6424 mL
100 mM 0.0206 mL 0.1028 mL 0.2056 mL 0.5139 mL
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CFTR corrector 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CFTR corrector 21628416-28-3CFTR corrector2CFTR corrector-2CFTRAutophagyCystic fibrosis transmembrane conductance regulatorInhibitorinhibitorinhibit

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