2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. CH5015765

CH5015765 is an orally available Hsp90 inhibitor bound to the N-terminal ATP binding site. CH5015765 plays an important role in cancer research.

For research use only. We do not sell to patients.

CH5015765 Chemical Structure

CH5015765 Chemical Structure

CAS No. : 959766-47-3

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CH5015765 Related Antibodies

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HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

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Description

CH5015765 is an orally available Hsp90 inhibitor bound to the N-terminal ATP binding site. CH5015765 plays an important role in cancer research[1].

IC50 & Target

HSP90

 

Molecular Weight

344.82

Formula

C16H13ClN4OS
CAS No.
SMILES

NC1=NC(C2=C(Cl)C=C3C4=C2C=CC=C4COC3)=NC(SC)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (145.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9001 mL 14.5003 mL 29.0006 mL
5 mM 0.5800 mL 2.9001 mL 5.8001 mL
View the Complete Stock Solution Preparation Table

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9001 mL 14.5003 mL 29.0006 mL 72.5016 mL
5 mM 0.5800 mL 2.9001 mL 5.8001 mL 14.5003 mL
10 mM 0.2900 mL 1.4500 mL 2.9001 mL 7.2502 mL
15 mM 0.1933 mL 0.9667 mL 1.9334 mL 4.8334 mL
20 mM 0.1450 mL 0.7250 mL 1.4500 mL 3.6251 mL
25 mM 0.1160 mL 0.5800 mL 1.1600 mL 2.9001 mL
30 mM 0.0967 mL 0.4833 mL 0.9667 mL 2.4167 mL
40 mM 0.0725 mL 0.3625 mL 0.7250 mL 1.8125 mL
50 mM 0.0580 mL 0.2900 mL 0.5800 mL 1.4500 mL
60 mM 0.0483 mL 0.2417 mL 0.4833 mL 1.2084 mL
80 mM 0.0363 mL 0.1813 mL 0.3625 mL 0.9063 mL
100 mM 0.0290 mL 0.1450 mL 0.2900 mL 0.7250 mL
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CH5015765 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CH5015765959766-47-3CH 5015765CH-5015765HSPHeat shock proteinsHCT116 cellsInhibitorinhibitorinhibit

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