Choline-d₄ chloride

Name: Choline-d 4 chloride
Brand: MedChemExpress
SKU: HY-B1337S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1337S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Choline-d₄ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

For research use only. We do not sell to patients.

Choline-d<sub>4</sub> chloride Chemical Structure

Choline-d₄ chloride Chemical Structure

CAS No. : 285979-70-6

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 112	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 179	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Choline-d₄ chloride:

Choline chloride In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Cholinesterase (ChE) Isoform Specific Products:

View All Isoforms

AChE BChE

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

143.65

Formula

C₅H₁₀D₄ClNO

CAS No.

285979-70-6

Unlabeled CAS

67-48-1

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])(O)C([N+](C)(C)C)([2H])[2H].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (696.14 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.9614 mL	34.8068 mL	69.6136 mL
5 mM	1.3923 mL	6.9614 mL	13.9227 mL
10 mM	0.6961 mL	3.4807 mL	6.9614 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (248 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.9614 mL	34.8068 mL	69.6136 mL	174.0341 mL
	5 mM	1.3923 mL	6.9614 mL	13.9227 mL	34.8068 mL
	10 mM	0.6961 mL	3.4807 mL	6.9614 mL	17.4034 mL
	15 mM	0.4641 mL	2.3205 mL	4.6409 mL	11.6023 mL
	20 mM	0.3481 mL	1.7403 mL	3.4807 mL	8.7017 mL
	25 mM	0.2785 mL	1.3923 mL	2.7845 mL	6.9614 mL
	30 mM	0.2320 mL	1.1602 mL	2.3205 mL	5.8011 mL
	40 mM	0.1740 mL	0.8702 mL	1.7403 mL	4.3509 mL
	50 mM	0.1392 mL	0.6961 mL	1.3923 mL	3.4807 mL
	60 mM	0.1160 mL	0.5801 mL	1.1602 mL	2.9006 mL
	80 mM	0.0870 mL	0.4351 mL	0.8702 mL	2.1754 mL
	100 mM	0.0696 mL	0.3481 mL	0.6961 mL	1.7403 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.