2. MAPK/ERK Pathway
  3. JNK
  4. CMX-8933

CMX-8933 is an octapeptide fragment of the goldfish brain neurotrophic factor ependymin. CMX-8933 increases the enzymatic activity of c-Jun N-terminal kinase (JNK), increases the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 can be used to study the role of ependymin in neuroplasticity, learning, memory formation, and neural regeneration.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CMX-8933 Chemical Structure

CMX-8933 Chemical Structure

CAS No. : 146877-90-9

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5 mg USD 350 In-stock
10 mg USD 550 In-stock
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Based on 1 publication(s) in Google Scholar

CMX-8933 Related Antibodies

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Description

CMX-8933 is an octapeptide fragment of the goldfish brain neurotrophic factor ependymin. CMX-8933 increases the enzymatic activity of c-Jun N-terminal kinase (JNK), increases the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 can be used to study the role of ependymin in neuroplasticity, learning, memory formation, and neural regeneration[1].

Molecular Weight

1049.22

Formula

C47H80N14O13
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Lys-Glu-Thr-Leu-Gln-Phe-Arg
Sequence Shortening

KKETLQFR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 30 mg/mL (28.59 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9531 mL 4.7654 mL 9.5309 mL
5 mM 0.1906 mL 0.9531 mL 1.9062 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.9531 mL 4.7654 mL 9.5309 mL 23.8272 mL
5 mM 0.1906 mL 0.9531 mL 1.9062 mL 4.7654 mL
10 mM 0.0953 mL 0.4765 mL 0.9531 mL 2.3827 mL
15 mM 0.0635 mL 0.3177 mL 0.6354 mL 1.5885 mL
20 mM 0.0477 mL 0.2383 mL 0.4765 mL 1.1914 mL
25 mM 0.0381 mL 0.1906 mL 0.3812 mL 0.9531 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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CMX-8933 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CMX-8933146877-90-9CMX8933CMX 8933JNKc-Jun N-terminal kinasePeptidesphosphorylationneural plasticitymemory formationInhibitorinhibitorinhibit

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