2. PROTAC
  3. Ligands for E3 Ligase
  4. CRBN ligand-9

CRBN ligand-9 (Compound 4d) is a CRBN ligand (Ki: 8.9 μM). CRBN ligand-9 can be used for synthesis of PROTACs.

For research use only. We do not sell to patients.

CRBN ligand-9 Chemical Structure

CRBN ligand-9 Chemical Structure

CAS No. : 55003-81-1

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CRBN ligand-9 Related Antibodies

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Description

CRBN ligand-9 (Compound 4d) is a CRBN ligand (Ki: 8.9 μM). CRBN ligand-9 can be used for synthesis of PROTACs[1][2].

Molecular Weight

303.23

Formula

C13H9N3O6
CAS No.
Appearance

Solid

Color

Off-white to gray

SMILES

O=C1NC(CCC1N2C(C3=CC=C(C=C3C2=O)[N+](=O)[O-])=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

COA (249 KB) HNMR (132 KB) LCMS (92 KB)

Handling Instructions (2659 KB)
References
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CRBN ligand-9 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CRBN ligand-955003-81-1CRBN ligand9CRBN ligand 9Ligands for E3 LigaseE3 ligase-recruiting MoietyCRBN ligandPROTACsInhibitorinhibitorinhibit

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