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  6. Darutoside

Darutoside is a diterpenoid isolated from Siegesbeckia.

For research use only. We do not sell to patients.

Darutoside Chemical Structure

Darutoside Chemical Structure

CAS No. : 59219-65-7

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5 mg USD 55 In-stock
10 mg USD 90 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Darutoside:

Darutoside Related Antibodies

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  • Purity & Documentation

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Description

Darutoside is a diterpenoid isolated from Siegesbeckia[1].

Cellular Effect
Cell Line Type Value Description References
MDA-MB-231 IC50
> 25 μM
Compound: 6
Inhibition of EGF-induced invasion of human MDA-MB-231 cells by MTT assay
Inhibition of EGF-induced invasion of human MDA-MB-231 cells by MTT assay
[PMID: 28302401]
RAW264.7 IC50
> 100 μM
Compound: 6
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 30 mins followed by LPS challenge measured after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 30 mins followed by LPS challenge measured after 24 hrs by Griess assay
[PMID: 28302401]
Molecular Weight

484.62

Formula

C26H44O8
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

C[C@]12[C@@]3([H])C(CC[C@]1([H])C(C)([C@H](O[C@]4([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)CC2)C)=C[C@]([C@@H](O)CO)(C)CC3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (206.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0635 mL 10.3174 mL 20.6347 mL
5 mM 0.4127 mL 2.0635 mL 4.1269 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0635 mL 10.3174 mL 20.6347 mL 51.5868 mL
5 mM 0.4127 mL 2.0635 mL 4.1269 mL 10.3174 mL
10 mM 0.2063 mL 1.0317 mL 2.0635 mL 5.1587 mL
15 mM 0.1376 mL 0.6878 mL 1.3756 mL 3.4391 mL
20 mM 0.1032 mL 0.5159 mL 1.0317 mL 2.5793 mL
25 mM 0.0825 mL 0.4127 mL 0.8254 mL 2.0635 mL
30 mM 0.0688 mL 0.3439 mL 0.6878 mL 1.7196 mL
40 mM 0.0516 mL 0.2579 mL 0.5159 mL 1.2897 mL
50 mM 0.0413 mL 0.2063 mL 0.4127 mL 1.0317 mL
60 mM 0.0344 mL 0.1720 mL 0.3439 mL 0.8598 mL
80 mM 0.0258 mL 0.1290 mL 0.2579 mL 0.6448 mL
100 mM 0.0206 mL 0.1032 mL 0.2063 mL 0.5159 mL
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Darutoside Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Darutoside59219-65-7OthersInhibitorinhibitorinhibit

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