2. Anti-infection
  3. HIV
  4. Decanoyl-RVKR-CMK

Decanoyl-RVKR-CMK  (Synonyms: DecRVKRcmk)

Cat. No.: HY-107760 Purity: 98.02%
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Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits over-expressed gp160 processing and HIV-1 replication.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Decanoyl-RVKR-CMK Chemical Structure

Decanoyl-RVKR-CMK Chemical Structure

CAS No. : 150113-99-8

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1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 1050 In-stock
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100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Decanoyl-RVKR-CMK:

Decanoyl-RVKR-CMK Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Decanoyl-RVKR-CMK

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HIV HIV-1 HIV-2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits over-expressed gp160 processing and HIV-1 replication[1].

In Vitro

Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell[1].
Decanoyl-RVKR-CMK (DecRVKRcmk) blocks regulated secretion of VGF[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Decanoyl-RVKR-CMK Related Antibodies

Cell Viability Assay[1]

Cell Line: HeLaCD4 cells infected with recombinant vaccinia viruses at a multiplicity of infection (MOI) of 5 PFU/mL.
Concentration: 35 and 70 µΜ.
Incubation Time: 7 days.
Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition).
Molecular Weight

744.41

Formula

C34H66ClN11O5
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (134.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3433 mL 6.7167 mL 13.4335 mL
5 mM 0.2687 mL 1.3433 mL 2.6867 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3433 mL 6.7167 mL 13.4335 mL 33.5836 mL
5 mM 0.2687 mL 1.3433 mL 2.6867 mL 6.7167 mL
10 mM 0.1343 mL 0.6717 mL 1.3433 mL 3.3584 mL
15 mM 0.0896 mL 0.4478 mL 0.8956 mL 2.2389 mL
20 mM 0.0672 mL 0.3358 mL 0.6717 mL 1.6792 mL
25 mM 0.0537 mL 0.2687 mL 0.5373 mL 1.3433 mL
30 mM 0.0448 mL 0.2239 mL 0.4478 mL 1.1195 mL
40 mM 0.0336 mL 0.1679 mL 0.3358 mL 0.8396 mL
50 mM 0.0269 mL 0.1343 mL 0.2687 mL 0.6717 mL
60 mM 0.0224 mL 0.1119 mL 0.2239 mL 0.5597 mL
80 mM 0.0168 mL 0.0840 mL 0.1679 mL 0.4198 mL
100 mM 0.0134 mL 0.0672 mL 0.1343 mL 0.3358 mL
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Decanoyl-RVKR-CMK Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Decanoyl-RVKR-CMK150113-99-8DecRVKRcmkHIVHuman immunodeficiency virusglycoproteinVGF glycoproteinVGFHIV-2 ROD infectionreplicationInhibitorinhibitorinhibit

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