2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. Dersimelagon phosphate

Dersimelagon phosphate  (Synonyms: MT-7117 phosphate)

Cat. No.: HY-109114A
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Dersimelagon phosphate is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon phosphate shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon phosphate can be used for the research of skin pigmentation.

For research use only. We do not sell to patients.

Dersimelagon phosphate Chemical Structure

Dersimelagon phosphate Chemical Structure

CAS No. : 2490660-87-0

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Other Forms of Dersimelagon phosphate:

Dersimelagon phosphate Related Antibodies

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Description

Dersimelagon phosphate is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon phosphate shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon phosphate can be used for the research of skin pigmentation[1][2].

Molecular Weight

773.75

Formula

C36H48F4N3O9P
CAS No.
SMILES

O=C(N1C[C@H](C2=C(N3CCC(C(O)=O)CC3)C=C(C(F)(F)F)C=C2)[C@@H](COC)C1)[C@]4([C@H](C5=CC=C(OC)C=C5)CN(C6CCCC6)C4)F.O=P(O)(O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dersimelagon phosphate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dersimelagon2490660-87-0MT-7117MT7117MT 7117Melanocortin ReceptorMC Receptorhumancynomolgus monkeymouseratskin pigmentationInhibitorinhibitorinhibit

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