2. Neuronal Signaling
  3. Cholinesterase (ChE) Monoamine Oxidase
  4. Desoxypeganine

Desoxypeganine  (Synonyms: Deoxypeganine; Deoxyvasicine)

Cat. No.: HY-108048
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Desoxypeganine (Deoxypeganine), an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine can be used for alcohol abuse research.

For research use only. We do not sell to patients.

Desoxypeganine Chemical Structure

Desoxypeganine Chemical Structure

CAS No. : 495-59-0

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Based on 1 publication(s) in Google Scholar

Other Forms of Desoxypeganine:

Desoxypeganine Related Antibodies

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Description

Desoxypeganine (Deoxypeganine), an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine can be used for alcohol abuse research[1].

IC50 & Target

BChE

2 μM (IC50)

AChE

17 μM (IC50)

MAO-A

2 μM (IC50)

In Vivo

Desoxypeganine (10-30 mg/kg, gavage, once daily for 16 days) reduced ethanol intake and ethanol preference dose-dependently[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Alko alcohol (AA) rats (Thirty eight adult)[1]
Dosage: 10, 20, 30 mg/kg
Administration: Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days
Result: Abolished ethanol preference.
Molecular Weight

172.23

Formula

C11H12N2
CAS No.
SMILES

C12=NC3=C(C=CC=C3)CN1CCC2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Desoxypeganine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desoxypeganine495-59-0Deoxypeganine DeoxyvasicineCholinesterase (ChE)Monoamine OxidaseMAOPeganum harmala L.butyrylcholinesteraseacetylcholinesteraseAlko alcoholalcohol abuseInhibitorinhibitorinhibit

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