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  3. DL-Lysine-d4 dihydrochloride

DL-Lysine-d4 dihydrochloride  (Synonyms: (±)-2,6-Diaminocaproic acid-d4 dihydrochloride)

Cat. No.: HY-B2236S Purity: ≥98.0%
SDS COA Handling Instructions

DL-Lysine-4,4,5,5-d4 (dihydrochloride) is the deuterium labeled DL-Lysine. DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins[1].

For research use only. We do not sell to patients.

DL-Lysine-d<sub>4</sub> dihydrochloride Chemical Structure

DL-Lysine-d4 dihydrochloride Chemical Structure

CAS No. : 284664-88-6

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5 mg USD 60 In-stock
10 mg USD 95 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DL-Lysine-d4 dihydrochloride:

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Description

DL-Lysine-4,4,5,5-d4 (dihydrochloride) is the deuterium labeled DL-Lysine. DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

223.13

Formula

C6H12D4Cl2N2O2

CAS No.
Unlabeled CAS

70-54-2

Appearance

Solid

Color

White to off-white

SMILES

NCC([2H])([2H])C([2H])([2H])CC(N)C(O)=O.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (448.17 mM; Need ultrasonic)

H2O : 100 mg/mL (448.17 mM; Need ultrasonic)

DMSO : 1 mg/mL (4.48 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4817 mL 22.4085 mL 44.8169 mL
5 mM 0.8963 mL 4.4817 mL 8.9634 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O / H2O 1 mM 4.4817 mL 22.4085 mL 44.8169 mL 112.0423 mL
H2O / H2O 5 mM 0.8963 mL 4.4817 mL 8.9634 mL 22.4085 mL
10 mM 0.4482 mL 2.2408 mL 4.4817 mL 11.2042 mL
15 mM 0.2988 mL 1.4939 mL 2.9878 mL 7.4695 mL
20 mM 0.2241 mL 1.1204 mL 2.2408 mL 5.6021 mL
25 mM 0.1793 mL 0.8963 mL 1.7927 mL 4.4817 mL
30 mM 0.1494 mL 0.7469 mL 1.4939 mL 3.7347 mL
40 mM 0.1120 mL 0.5602 mL 1.1204 mL 2.8011 mL
50 mM 0.0896 mL 0.4482 mL 0.8963 mL 2.2408 mL
60 mM 0.0747 mL 0.3735 mL 0.7469 mL 1.8674 mL
80 mM 0.0560 mL 0.2801 mL 0.5602 mL 1.4005 mL
100 mM 0.0448 mL 0.2241 mL 0.4482 mL 1.1204 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DL-Lysine-d4 dihydrochloride
Cat. No.:
HY-B2236S
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