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DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity.

For research use only. We do not sell to patients.

DS21360717 Chemical Structure

DS21360717 Chemical Structure

CAS No. : 2304654-43-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 715 In-stock
Solution
10 mM * 1 mL in DMSO USD 715 In-stock
Solid
1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 1050 In-stock
25 mg USD 2100 In-stock
50 mg USD 3400 In-stock
100 mg USD 5500 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

DS21360717 Related Antibodies

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1 Publications Citing Use of MCE DS21360717

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  • Customer Review

Description

DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity[1].

Molecular Weight

389.45

Formula

C21H23N7O
CAS No.
Appearance

Solid

SMILES

N[C@H]1CCCC[C@H]1NC2=NC(NC3=CC(C)=CC=C3)=C4C(C=NNC4=O)=C2C#N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (513.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5677 mL 12.8386 mL 25.6772 mL
5 mM 0.5135 mL 2.5677 mL 5.1354 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.93%

COA (256 KB) HNMR (564 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5677 mL 12.8386 mL 25.6772 mL 64.1931 mL
5 mM 0.5135 mL 2.5677 mL 5.1354 mL 12.8386 mL
10 mM 0.2568 mL 1.2839 mL 2.5677 mL 6.4193 mL
15 mM 0.1712 mL 0.8559 mL 1.7118 mL 4.2795 mL
20 mM 0.1284 mL 0.6419 mL 1.2839 mL 3.2097 mL
25 mM 0.1027 mL 0.5135 mL 1.0271 mL 2.5677 mL
30 mM 0.0856 mL 0.4280 mL 0.8559 mL 2.1398 mL
40 mM 0.0642 mL 0.3210 mL 0.6419 mL 1.6048 mL
50 mM 0.0514 mL 0.2568 mL 0.5135 mL 1.2839 mL
60 mM 0.0428 mL 0.2140 mL 0.4280 mL 1.0699 mL
80 mM 0.0321 mL 0.1605 mL 0.3210 mL 0.8024 mL
100 mM 0.0257 mL 0.1284 mL 0.2568 mL 0.6419 mL
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DS21360717 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DS213607172304654-43-9DS 21360717DS-21360717OthersInhibitorinhibitorinhibit

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