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  3. FKBP PROTACs
  4. dTAGV-1 hydrochloride

dTAGV-1 hydrochloride is the hydrochloride form of dTAGV-1 that is a small molecule degrader of FKBP12.

For research use only. We do not sell to patients.

dTAGV-1 hydrochloride Chemical Structure

dTAGV-1 hydrochloride Chemical Structure

CAS No. : 2624313-16-0

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5 mg USD 450 In-stock
10 mg USD 765 In-stock
25 mg USD 1600 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of dTAGV-1 hydrochloride:

dTAGV-1 hydrochloride Related Antibodies

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Description

dTAGV-1 hydrochloride is the hydrochloride form of dTAGV-1 that is a small molecule degrader of FKBP12[1].

Molecular Weight

1284.00

Formula

C68H91ClN6O14S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H]1N(CCCC1)C([C@H](C2=CC(OC)=C(C(OC)=C2)OC)CC)=O)O[C@@H](C3=C(C=CC=C3)OCC(NCCCCCCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)=O)=O)=O)CCC7=CC(OC)=C(C=C7)OC.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (77.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7788 mL 3.8941 mL 7.7882 mL
5 mM 0.1558 mL 0.7788 mL 1.5576 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7788 mL 3.8941 mL 7.7882 mL 19.4704 mL
5 mM 0.1558 mL 0.7788 mL 1.5576 mL 3.8941 mL
10 mM 0.0779 mL 0.3894 mL 0.7788 mL 1.9470 mL
15 mM 0.0519 mL 0.2596 mL 0.5192 mL 1.2980 mL
20 mM 0.0389 mL 0.1947 mL 0.3894 mL 0.9735 mL
25 mM 0.0312 mL 0.1558 mL 0.3115 mL 0.7788 mL
30 mM 0.0260 mL 0.1298 mL 0.2596 mL 0.6490 mL
40 mM 0.0195 mL 0.0974 mL 0.1947 mL 0.4868 mL
50 mM 0.0156 mL 0.0779 mL 0.1558 mL 0.3894 mL
60 mM 0.0130 mL 0.0649 mL 0.1298 mL 0.3245 mL
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dTAGV-1 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

dTAGV-12624313-16-0dTAGV1dTAGV 1FKBPPROTACsFK506-binding proteinhydrochlorideFKBP12degradercancerInhibitorinhibitorinhibit

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