2. Fluorescent Dye
  3. Cell Staining Analysis
  4. Cell Function Analysiss
  5. Nucleic Acid Dyes

Nucleic Acid Dyes

Nucleic Acid Dyes (76):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-D0815
    Propidium Iodide 25535-16-4 99.69%
    Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
    Propidium Iodide
  • HY-101879
    Acridine Orange hydrochloride 65-61-2 99.86%
    Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm).
    Acridine Orange hydrochloride
  • HY-110251
    DFHBI-1T 1539318-36-9 98.12%
    DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells.
    DFHBI-1T
  • HY-D0150
    Thiazole Orange 107091-89-4 99.56%
    Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively.
    Thiazole Orange
  • HY-D0903
    1,8-Diazafluoren-9-one 54078-29-4 99.74%
    1,8-Diazafluoren-9-one (DFO) is a chemical that is used to find fingerprints on porous surfaces.
    1,8-Diazafluoren-9-one
  • HY-D0971
    Pyronin Y 92-32-0
    Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells.
    Pyronin Y
  • HY-100575
    Acriflavine 8048-52-0 ≥98.0%
    Acriflavine is a fluorescent dye for labeling high molecular weight RNA. It is also a topical antiseptic.
    Acriflavine
  • HY-66021
    6-FAM 3301-79-9 99.88%
    6-FAM (6-Carboxyfluorescein) is an isomer of carboxyfluorescein and is mainly used for sequencing and labeling of nucleic acids.
    6-FAM
  • HY-D1020
    7-Aminoactinomycin D 7240-37-1 ≥99.0%
    7-Aminoactinomycin D (7-AAD) a fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects.
    7-Aminoactinomycin D
  • HY-15944
    5(6)-TAMRA 98181-63-6 99.72%
    5(6)-TAMRA is a fluorescent dye molecule widely used as a label for peptides and proteins.
    5(6)-TAMRA
  • HY-136277
    DFHO 1420815-34-4 99.83%
    DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells.
    DFHO
  • HY-D0913
    1-Methyl-7-nitroisatoic anhydride 73043-80-8 ≥98.0%
    1-methyl-7-nitroisatoic anhydride (1M7) is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity, can be used for RNA structure analysis.
    1-Methyl-7-nitroisatoic anhydride
  • HY-D0987
    Stains-All 7423-31-6 99.91%
    Stains-All, a cationic carbocyanine dye, is a convenient probe to study the structural features of the individual calcium-binding sites of calmodulin (CaM) and related calcium-binding proteins (CaBP).
    Stains-All
  • HY-W012642
    2-Aminopurine 452-06-2 99.54%
    2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics.
    2-Aminopurine
  • HY-B0883
    Proflavine hemisulfate 1811-28-5 98.45%
    Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent. Proflavine hemisulfate behaves as a pore blocker for Kir3.2. Proflavine hemisulfate is a potential lead compound for Kir3.2-associated neurological diseases.
    Proflavine hemisulfate
  • HY-D0952
    Acridine Orange base 494-38-2
    Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays.
    Acridine Orange base
  • HY-D1200
    Malachite Green Carbinol base 510-13-4
    Malachite Green Carbinol base (MGOH, MGCB) is a derivative of Malachite green (MG) with not fluorescence. Malachite green carbinol base (MGOH, MGCB), as a pH regulation reagent, MGCB molecule could release OH- under UV light irradiation and generate a progressive shift in pH values. MGCB solution turns from colorless to deep green rapidly when exposed to a high-pressure UV lamp (500 W, 50 W/cm).
    Malachite Green Carbinol base
  • HY-D0996
    LDS-751 181885-68-7 99.30%
    Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 is a nucleic acid stain that mainly detects DNA. Lds-751 has a high affinity for DNA and fluorescence is enhanced after binding, but the maximum emission wavelength is 670nm. Lds-751 and Thiazole orange can be used for the differentiation of red blood cells, platelets, reticulocytes, and nucleated cells and can be stimulated at 488nm. Studies have shown that LDS-751 binds almost exclusively to mitochondria when incubated with nucleated living cells. After nucleated Acridine Orange (HY-101879) staining and LDS-751 treatment of cells, confocal microscopy revealed almost no co-location of the cells. Staining with Rhodamine 123 (HY-D0816), a dye known to bind polarized mitochondria, was almost identical to the pattern observed with LDS-751.
    LDS-751
  • HY-D0163
    Methyl Green 14855-76-6
    Methyl Green is a potent fluorescent dye. Methyl Green is a DNA stains of cells and electrophoretic gels. Methyl Green can be used as a stain for direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm.
    Methyl Green
  • HY-D0053
    6-ROX 194785-18-7 99.00%
    6-ROX, a fluorescent marker of oligonucleotides, acts as a receptor coupled to 5-FAM and as a donor in FRET imaging. Excitation wavelength: 568nm. Emission wavelength: 568nm.
    6-ROX