2. Cell Cycle/DNA Damage
  3. CDK
  4. Eciruciclib

Eciruciclib is an antineoplastic and potent cyclin dependent kinase (CDK) inhibitor.

For research use only. We do not sell to patients.

Eciruciclib Chemical Structure

Eciruciclib Chemical Structure

CAS No. : 1868086-40-1

Size Price Stock Quantity
1 mg USD 168 In-stock
5 mg USD 420 In-stock
10 mg USD 635 In-stock
25 mg USD 1080 In-stock
50 mg USD 1500 In-stock
100 mg USD 1980 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Eciruciclib Related Antibodies

Top Publications Citing Use of Products

View All CDK Isoform Specific Products:

View All Isoforms
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • Biological Activity

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Description

Eciruciclib is an antineoplastic and potent cyclin dependent kinase (CDK) inhibitor[1].

Molecular Weight

488.60

Formula

C27H33FN8
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

FC1=C(C2=CC3=C(C(C)C)N(C)N=C3C=C2)N=C(NC4=NC=C(CN5CCN(CC5)CC)C=C4)N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (4.09 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0467 mL 10.2333 mL 20.4666 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.18%

COA (243 KB) HNMR (129 KB) RP-HPLC (485 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0467 mL 10.2333 mL 20.4666 mL 51.1666 mL
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Eciruciclib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eciruciclib1868086-40-1CDKCyclin dependent kinaseInhibitorinhibitorinhibit

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