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Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis.

For research use only. We do not sell to patients.

Eprodisate Chemical Structure

Eprodisate Chemical Structure

CAS No. : 21668-77-9

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 52 In-stock
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Liquid
500 mg USD 50 In-stock
1 g   Get quote  
5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2].

Molecular Weight

204.22

Formula

C3H8O6S2

CAS No.
Appearance

Liquid (Density: 1.33 g/cm3)

Color

Colorless to light yellow

SMILES

O=S(CCCS(=O)(O)=O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (612.09 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8967 mL 24.4834 mL 48.9668 mL
5 mM 0.9793 mL 4.8967 mL 9.7934 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.8967 mL 24.4834 mL 48.9668 mL 122.4170 mL
5 mM 0.9793 mL 4.8967 mL 9.7934 mL 24.4834 mL
10 mM 0.4897 mL 2.4483 mL 4.8967 mL 12.2417 mL
15 mM 0.3264 mL 1.6322 mL 3.2645 mL 8.1611 mL
20 mM 0.2448 mL 1.2242 mL 2.4483 mL 6.1209 mL
25 mM 0.1959 mL 0.9793 mL 1.9587 mL 4.8967 mL
30 mM 0.1632 mL 0.8161 mL 1.6322 mL 4.0806 mL
40 mM 0.1224 mL 0.6121 mL 1.2242 mL 3.0604 mL
50 mM 0.0979 mL 0.4897 mL 0.9793 mL 2.4483 mL
60 mM 0.0816 mL 0.4081 mL 0.8161 mL 2.0403 mL
80 mM 0.0612 mL 0.3060 mL 0.6121 mL 1.5302 mL
100 mM 0.0490 mL 0.2448 mL 0.4897 mL 1.2242 mL
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Product Name:
Eprodisate
Cat. No.:
HY-128849
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