2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Endogenous Metabolite
  4. Evernic Acid

Evernic Acid is a secondary metabolite generated by lichens, including Ramalina, Evernia, and Hypogymnia, and several studies have described its anticancer, antifungal, and antimicrobial effects. Neuroprotective and anti-inflammatory effects.

For research use only. We do not sell to patients.

Evernic Acid Chemical Structure

Evernic Acid Chemical Structure

CAS No. : 537-09-7

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5 mg USD 85 In-stock
10 mg USD 140 In-stock
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Based on 1 publication(s) in Google Scholar

Evernic Acid Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Evernic Acid is a secondary metabolite generated by lichens, including Ramalina, Evernia, and Hypogymnia, and several studies have described its anticancer, antifungal, and antimicrobial effects. Neuroprotective and anti-inflammatory effects[1].

IC50 & Target[1]

Fungal Metabolite

 

Cellular Effect
Cell Line Type Value Description References
Huh-7 IC50
> 100 μM
Compound: 1
Cytotoxicity against human Huh7.5 cells after 24 hrs by Cell-titerGlo luminescence assay
Cytotoxicity against human Huh7.5 cells after 24 hrs by Cell-titerGlo luminescence assay
[PMID: 23806111]
Huh-7 IC50
77.3 μM
Compound: 1
Antiplasmodial activity against liver stage of Plasmodium berghei ANKA expressing GFP infected in human Huh7.5 cells assessed as reduction in PB18S gene expression after 48 hrs by qRT-PCR analysis
Antiplasmodial activity against liver stage of Plasmodium berghei ANKA expressing GFP infected in human Huh7.5 cells assessed as reduction in PB18S gene expression after 48 hrs by qRT-PCR analysis
[PMID: 23806111]
KB IC50
190.4 μM
Compound: 1
Cytotoxicity against human KB cells after 72 hrs by Alamar Blue assay
Cytotoxicity against human KB cells after 72 hrs by Alamar Blue assay
[PMID: 23806111]
Molecular Weight

332.30

Formula

C17H16O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=CC(OC(C2=C(C=C(C=C2O)OC)C)=O)=CC(O)=C1C(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (30.09 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0093 mL 15.0466 mL 30.0933 mL
5 mM 0.6019 mL 3.0093 mL 6.0187 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0093 mL 15.0466 mL 30.0933 mL 75.2332 mL
5 mM 0.6019 mL 3.0093 mL 6.0187 mL 15.0466 mL
10 mM 0.3009 mL 1.5047 mL 3.0093 mL 7.5233 mL
15 mM 0.2006 mL 1.0031 mL 2.0062 mL 5.0155 mL
20 mM 0.1505 mL 0.7523 mL 1.5047 mL 3.7617 mL
25 mM 0.1204 mL 0.6019 mL 1.2037 mL 3.0093 mL
30 mM 0.1003 mL 0.5016 mL 1.0031 mL 2.5078 mL
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Evernic Acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Evernic Acid537-09-7BacterialEndogenous Metabolitesecondary metaboliteanticancerantifungalantimicrobial effectsneuroprotectiveanti-Inflammatory effectsInhibitorinhibitorinhibit

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