2. Others Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. Isotope-Labeled Compounds ADC Cytotoxin Topoisomerase
  4. Exatecan Intermediate 1-d5

Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1.

For research use only. We do not sell to patients.

Exatecan Intermediate 1-d<sub>5</sub> Chemical Structure

Exatecan Intermediate 1-d5 Chemical Structure

CAS No. : 1346617-23-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Exatecan Intermediate 1-d5:

Exatecan Intermediate 1-d5 Related Antibodies

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Description

Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Exatecan Intermediate 1-d5 Related Antibodies
Molecular Weight

268.28

Formula

C13H8D5NO5
CAS No.
Unlabeled CAS

110351-94-5
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C1N2C(C(CC2)=O)=CC([C@@](C([2H])(C([2H])([2H])[2H])[2H])3O)=C1COC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.90%

SDS (393 KB)

COA (262 KB) HNMR (229 KB) RP-HPLC (364 KB) LCMS (98 KB)

Handling Instructions (2659 KB)
References
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Exatecan Intermediate 1-d5 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Exatecan Intermediate 1-d51346617-23-9Isotope-Labeled CompoundsADC CytotoxinTopoisomeraseADC PayloadInhibitorinhibitorinhibit

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