2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Cytotoxin Topoisomerase
  4. Exatecan Intermediate 4

Exatecan Intermediate 4 (compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers.

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Exatecan Intermediate 4 Chemical Structure

Exatecan Intermediate 4 Chemical Structure

CAS No. : 2436720-50-0

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Other Forms of Exatecan Intermediate 4:

Exatecan Intermediate 4 Related Antibodies

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Description

Exatecan Intermediate 4 (compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1][2].

IC50 & Target

Camptothecins

 

Molecular Weight

244.69

Formula

C11H14ClFN2O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC1=C2CCC(C(C2=C(C=C1F)N)=O)N.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation
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Exatecan Intermediate 4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Exatecan Intermediate 42436720-50-0Exatecan Intermediate4Exatecan Intermediate-4ADC CytotoxinTopoisomeraseADC PayloadInhibitorinhibitorinhibit

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