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  3. FAM49B (190-198) mouse

FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission. FAM49B regulates mitochondrial function and integrity and tumor progression. FAM49B is also a negative regulator in T cell activation, it acts by repressing GTPase Rac activity and modulating cytoskeleton reorganization.

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FAM49B (190-198) mouse Chemical Structure

FAM49B (190-198) mouse Chemical Structure

CAS No. : 1588388-60-6

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Description

FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission. FAM49B regulates mitochondrial function and integrity and tumor progression. FAM49B is also a negative regulator in T cell activation, it acts by repressing GTPase Rac activity and modulating cytoskeleton reorganization[1].

Molecular Weight

1042.20

Formula

C49H71N9O14S

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Phe-Tyr-Ala-Glu-Ala-Thr-Pro-Met-Leu

Sequence Shortening

FYAEATPML

SMILES

O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC3=CC=CC=C3)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (47.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9595 mL 4.7975 mL 9.5951 mL
5 mM 0.1919 mL 0.9595 mL 1.9190 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9595 mL 4.7975 mL 9.5951 mL 23.9877 mL
5 mM 0.1919 mL 0.9595 mL 1.9190 mL 4.7975 mL
10 mM 0.0960 mL 0.4798 mL 0.9595 mL 2.3988 mL
15 mM 0.0640 mL 0.3198 mL 0.6397 mL 1.5992 mL
20 mM 0.0480 mL 0.2399 mL 0.4798 mL 1.1994 mL
25 mM 0.0384 mL 0.1919 mL 0.3838 mL 0.9595 mL
30 mM 0.0320 mL 0.1599 mL 0.3198 mL 0.7996 mL
40 mM 0.0240 mL 0.1199 mL 0.2399 mL 0.5997 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FAM49B (190-198) mouse
Cat. No.:
HY-P10650
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