1. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  2. Ferroptosis Reactive Oxygen Species
  3. Ferroptosis inducer-2

Ferroptosis inducer-2 (Compound 24) is an inducer for heme oxygenase-1 (HO-1). Ferroptosis inducer-2 exhibits anticancer activity against triple-negative breast cancer (TNBC) cells through induction of ferroptosis.

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Ferroptosis inducer-2 Chemical Structure

Ferroptosis inducer-2 Chemical Structure

CAS No. : 28657-88-7

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5 mg USD 160 In-stock
10 mg USD 270 In-stock
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50 mg USD 700 In-stock
100 mg USD 1120 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Ferroptosis inducer-2 (Compound 24) is an inducer for heme oxygenase-1 (HO-1). Ferroptosis inducer-2 exhibits anticancer activity against triple-negative breast cancer (TNBC) cells through induction of ferroptosis[1].

Molecular Weight

291.34

Formula

C19H17NO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OCCC1=CNC2=C1C=CC=C2)/C=C/C3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (686.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4324 mL 17.1621 mL 34.3242 mL
5 mM 0.6865 mL 3.4324 mL 6.8648 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4324 mL 17.1621 mL 34.3242 mL 85.8104 mL
5 mM 0.6865 mL 3.4324 mL 6.8648 mL 17.1621 mL
10 mM 0.3432 mL 1.7162 mL 3.4324 mL 8.5810 mL
15 mM 0.2288 mL 1.1441 mL 2.2883 mL 5.7207 mL
20 mM 0.1716 mL 0.8581 mL 1.7162 mL 4.2905 mL
25 mM 0.1373 mL 0.6865 mL 1.3730 mL 3.4324 mL
30 mM 0.1144 mL 0.5721 mL 1.1441 mL 2.8603 mL
40 mM 0.0858 mL 0.4291 mL 0.8581 mL 2.1453 mL
50 mM 0.0686 mL 0.3432 mL 0.6865 mL 1.7162 mL
60 mM 0.0572 mL 0.2860 mL 0.5721 mL 1.4302 mL
80 mM 0.0429 mL 0.2145 mL 0.4291 mL 1.0726 mL
100 mM 0.0343 mL 0.1716 mL 0.3432 mL 0.8581 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ferroptosis inducer-2
Cat. No.:
HY-161601
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