1. Metabolic Enzyme/Protease
  2. Adenosine Deaminase
  3. FR221647

FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM.

For research use only. We do not sell to patients.

FR221647 Chemical Structure

FR221647 Chemical Structure

CAS No. : 256461-28-6

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Description

FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM[1].

In Vitro

FR221647 is an inhibitor of human adenosine deaminase (ADA) with a Ki value of 5.9 μM[1]. FR221647 is not cytotoxic at a concentration of 100 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

259.30

Formula

C14H17N3O2

CAS No.
SMILES

O=C(C1=CN(C(CO)CCC2=CC=CC=C2)C=N1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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FR221647
Cat. No.:
HY-120248
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