2. Metabolic Enzyme/Protease
  3. Glucosidase
  4. GCase modulator-1

GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC50=2.23 μM).

For research use only. We do not sell to patients.

GCase modulator-1 Chemical Structure

GCase modulator-1 Chemical Structure

CAS No. : 796079-91-9

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GCase modulator-1 Related Antibodies

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Description

GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC50=2.23 μM)[1].

IC50 & Target

AC50: 2.23 μM (Glucosidase)[1]
Molecular Weight

338.41

Formula

C22H18N4
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

C1(C2=NC3=C(C(N4CC5=C(CC4)C=CC=C5)=N2)C=CC=C3)=CN=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (59.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9550 mL 14.7750 mL 29.5500 mL
5 mM 0.5910 mL 2.9550 mL 5.9100 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9550 mL 14.7750 mL 29.5500 mL 73.8749 mL
5 mM 0.5910 mL 2.9550 mL 5.9100 mL 14.7750 mL
10 mM 0.2955 mL 1.4775 mL 2.9550 mL 7.3875 mL
15 mM 0.1970 mL 0.9850 mL 1.9700 mL 4.9250 mL
20 mM 0.1477 mL 0.7387 mL 1.4775 mL 3.6937 mL
25 mM 0.1182 mL 0.5910 mL 1.1820 mL 2.9550 mL
30 mM 0.0985 mL 0.4925 mL 0.9850 mL 2.4625 mL
40 mM 0.0739 mL 0.3694 mL 0.7387 mL 1.8469 mL
50 mM 0.0591 mL 0.2955 mL 0.5910 mL 1.4775 mL
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GCase modulator-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GCase modulator-1796079-91-9GCase modulator1GCase modulator 1GlucosidaseInhibitorinhibitorinhibit

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