SBK3 - SH3 domain binding kinase family member 3 Gene

Homo sapiens

Also known as SGK110

Gene ID: 100130827 | Gene type: protein coding

About SBK3

This gene has 2 transcripts (splice variants), 82 orthologues and 1 paralogue. Biased expression in heart (RPKM 5.3), fat (RPKM 0.8) and 1 other tissue.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

SBK3 Products(1)

mRNA	Protein	Name
NM_001199824.2	NP_001186753.1	uncharacterized serine/threonine-protein kinase SBK3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SBK3 Protein Structure

Pkinase

0
100
200
300
400
423 a.a.

Protein Preferred Names

Protein Names

uncharacterized serine/threonine-protein kinase SBK3

SH3-binding domain kinase family member 3

SBK3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SBK3	P0C264	C1orf105	Homo sapiens	O95561	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	C1orf105	Homo sapiens	O95561	Y2H Array	32296183
Intra	SBK3	P0C264	POLDIP3	Homo sapiens	Q8WUT1	Validated Y2H	32296183
Intra	SBK3	P0C264	POLDIP3	Homo sapiens	Q8WUT1	Y2H Array	32296183
Intra	SBK3	P0C264	POLDIP3	Homo sapiens	Q8WUT1	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	MBD3L2	Homo sapiens	Q8NHZ7	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	MBD3L2	Homo sapiens	Q8NHZ7	Y2H Array	32296183
Intra	SBK3	P0C264	MBD3L2	Homo sapiens	Q8NHZ7	Validated Y2H	32296183
Intra	SBK3	P0C264	TNNT1	Homo sapiens	P13805-3	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	TNNT1	Homo sapiens	P13805-3	Validated Y2H	32296183
Intra	SBK3	P0C264	TNNT1	Homo sapiens	P13805-3	Y2H Array	32296183
Intra	SBK3	P0C264	SNRNP35	Homo sapiens	Q16560-2	Validated Y2H	32296183
Intra	SBK3	P0C264	SNRNP35	Homo sapiens	Q16560-2	Y2H Array	32296183
Intra	SBK3	P0C264	SNRNP35	Homo sapiens	Q16560-2	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	NOTO	Homo sapiens	A8MTQ0	Y2H Array	32296183
Intra	SBK3	P0C264	NOTO	Homo sapiens	A8MTQ0	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	CRY2	Homo sapiens	Q49AN0	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	CRY2	Homo sapiens	Q49AN0	Y2H Array	32296183
Intra	SBK3	P0C264	CRY2	Homo sapiens	Q49AN0	Validated Y2H	32296183
Intra	SBK3	P0C264	EXOSC2	Homo sapiens	Q13868	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	EXOSC2	Homo sapiens	Q13868	Y2H Array	32296183
Intra	SBK3	P0C264	EXOSC2	Homo sapiens	Q13868	Validated Y2H	32296183
Intra	SBK3	P0C264	SMAD3	Homo sapiens	P84022	Y2H Array	32296183
Intra	SBK3	P0C264	SMAD3	Homo sapiens	P84022	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	SMAD3	Homo sapiens	P84022	Validated Y2H	32296183
Intra	SBK3	P0C264	DMAP1	Homo sapiens	Q9NPF5	Validated Y2H	32296183
Intra	SBK3	P0C264	DMAP1	Homo sapiens	Q9NPF5	Y2H Array	32296183
Intra	SBK3	P0C264	DMAP1	Homo sapiens	Q9NPF5	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	AIMP2	Homo sapiens	Q13155	Validated Y2H	32296183
Intra	SBK3	P0C264	GATAD2B	Homo sapiens	Q8WXI9	Y2H Prey Pooling	32296183
Intra	SBK3	P0C264	GATAD2B	Homo sapiens	Q8WXI9	Validated Y2H	32296183
Intra	SBK3	P0C264	GATAD2B	Homo sapiens	Q8WXI9	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Familial Atrial Fibrillation

Atrial Fibrillation, Familial	Atfb
Atrial Fibrillation Autosomal Dominant	Autosomal Dominant Atrial Fibrillation
Auricular Fibrillation	Atrial Fibrillation
Atrial Fibrillation, Familial, 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12468	SBK3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SBK3	RGD	RGD:1583965
Felis catus	SBK3	VGNC	VGNC:64888
Macaca mulatta	SBK3	VGNC	VGNC:82231
Mus musculus	SBK3	MGD	MGI:2685924
Canis familiaris	SBK3	VGNC	VGNC:45883
Others	SBK3	NCBI

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