2. Gene
  3. NOTO - notochord homeobox Gene

NOTO - notochord homeobox Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 344022 | Gene type: protein coding

About NOTO

This gene has 1 transcript (splice variant), 90 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in central nervous system development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryonic organ development; motile cilium assembly; and regulation of cilium assembly. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NOTO Products(1)

mRNA Protein Name
NM_001134462.2 NP_001127934.1 homeobox protein notochord

NOTO Protein Structure

Homeobox

Homeobox: Homeobox domain (157 - 213)

  • 0
  • 100
  • 200
  • 251 a.a.
Protein Preferred Names Protein Names

homeobox protein notochord

notochord homolog

NOTO Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra NOTO A8MTQ0 FAM9B Homo sapiens Q8IZU0
Validated Y2H
32296183
Intra NOTO A8MTQ0 CHAF1A Homo sapiens Q13111
Validated Y2H
32296183
Intra NOTO A8MTQ0 PIH1D2 Homo sapiens Q8WWB5
Validated Y2H
32296183
Intra NOTO A8MTQ0 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra NOTO A8MTQ0 KRTAP19-7 Homo sapiens Q3SYF9
Validated Y2H
32296183
Intra NOTO A8MTQ0 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra NOTO A8MTQ0 KRTAP5-6 Homo sapiens Q6L8G9
Validated Y2H
32296183
Intra NOTO A8MTQ0 KRT34 Homo sapiens O76011
Validated Y2H
32296183
Intra NOTO A8MTQ0 BTF3 Homo sapiens P20290-2
Validated Y2H
32296183
Intra NOTO A8MTQ0 EIPR1 Homo sapiens Q53HC9
Y2H Prey Pooling
32296183
Intra NOTO A8MTQ0 EIPR1 Homo sapiens Q53HC9
Y2H Array
32296183
Intra NOTO A8MTQ0 EIPR1 Homo sapiens Q53HC9
Validated Y2H
32296183
Intra NOTO A8MTQ0 IP6K3 Homo sapiens Q96PC2
Validated Y2H
32296183
Intra NOTO A8MTQ0 BANP Homo sapiens Q8N9N5-2
Validated Y2H
32296183
Intra NOTO A8MTQ0 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra NOTO A8MTQ0 KRTAP6-1 Homo sapiens Q3LI64
Validated Y2H
32296183
Intra NOTO A8MTQ0 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra NOTO A8MTQ0 APOBEC1 Homo sapiens P41238
Validated Y2H
32296183
Intra NOTO A8MTQ0 SBK3 Homo sapiens P0C264
Validated Y2H
32296183
Intra NOTO A8MTQ0 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra NOTO A8MTQ0 UBTFL1 Homo sapiens P0CB47
Validated Y2H
32296183
Intra NOTO A8MTQ0 POU4F2 Homo sapiens Q12837
Validated Y2H
32296183
Intra NOTO A8MTQ0 FOXD2 Homo sapiens O60548
Validated Y2H
32296183
Intra NOTO A8MTQ0 ETV3L Homo sapiens Q6ZN32
Validated Y2H
32296183
Intra NOTO A8MTQ0 FOXH1 Homo sapiens O75593
Validated Y2H
32296183
Intra NOTO A8MTQ0 LRP10 Homo sapiens Q7Z4F1
Validated Y2H
32296183
Intra NOTO A8MTQ0 HNRNPK Homo sapiens P61978-2
Validated Y2H
32296183
Intra NOTO A8MTQ0 MAGED1 Homo sapiens Q9Y5V3
Validated Y2H
32296183
Intra NOTO A8MTQ0 CEP19 Homo sapiens Q96LK0
Validated Y2H
32296183
Intra NOTO A8MTQ0 CCDC120 Homo sapiens Q96HB5
Validated Y2H
32296183
Intra NOTO A8MTQ0 BAG3 Homo sapiens O95817
Validated Y2H
32296183
Intra NOTO A8MTQ0 LDLRAP1 Homo sapiens Q5SW96
Validated Y2H
32296183
Intra NOTO A8MTQ0 GLYCTK Homo sapiens Q8IVS8
Validated Y2H
32296183
Intra NOTO A8MTQ0 MEIS2 Homo sapiens O14770-4
Validated Y2H
32296183
Intra NOTO A8MTQ0 TTC23 Homo sapiens Q5W5X9-3
Validated Y2H
32296183
Intra NOTO A8MTQ0 NKX2-4 Homo sapiens Q9H2Z4
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Epilepsy, Familial Temporal Lobe, 4

ETL4

Epilepsy, Occipitotemporal Lobe, And Migraine With Aura

Epolm

Familial Temporal Lobe Epilepsy 4

Occipitotemporal Lobe Epilepsy And Migraine With Aura
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09453 NOTO Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NOTO RGD RGD:1562910
Macaca mulatta NOTO VGNC VGNC:106189
Bos taurus NOTO VGNC VGNC:32180
Mus musculus NOTO MGD MGI:3053002