2. Gene
  3. CTLA4 - cytotoxic T-lymphocyte associated protein 4 Gene

CTLA4 - cytotoxic T-lymphocyte associated protein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca fascicularis
Gene ID: 102115124 | Gene type: protein coding

About CTLA4

Primary_assembly 12: 91,640,701-91,646,819 forward strand.Macaca_fascicularis_6.0:CM021950.1

This gene has 2 transcripts (splice variants), 157 orthologues and 1 paralogue.

CTLA4 Products(2)

mRNA Protein Name
XM_005574017.3 XP_005574074.1 cytotoxic T-lymphocyte protein 4 isoform X2
XM_005574014.3 XP_005574071.1 cytotoxic T-lymphocyte protein 4 isoform X1

CTLA4 Protein Structure

IgV_CTLA-4

IgV_CTLA-4: cd05721 (38 - 59)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (38 - 152)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (38 - 41)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (44 - 47)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (51 - 59)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (60 - 67)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (68 - 75)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (68 - 74)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (75 - 96)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (79 - 88)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (93 - 96)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (102 - 131)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (102 - 107)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (110 - 116)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (124 - 131)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (132 - 138)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (139 - 152)

IgV_CTLA-4

IgV_CTLA-4: cd05721 (139 - 151)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

cytotoxic T-lymphocyte protein 4

Recombinant CTLA4 Proteins

Cat. No. Product Name Accession Purity
HY-P7838 CTLA-4 Protein, Cynomolgus (HEK293, His) G7PL88 (A37-S160) ≥95%

Related Agents

Approval
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9901 Ipilimumab Inhibitor 99.88% Unkown
HY-108829 Abatacept ≥99.0% Unkown
HY-P9918 Tremelimumab 99.50% Unkown
Clinical Phase
Inhibitory Antibodies (10)
Cat. No. Product Name Effect
Purity Phase
HY-P99117 Cadonilimab Inhibitor / Phase 3
HY-P99484 Botensilimab Inhibitor 97.18% Phase 3
HY-P990042 Gotistobart Inhibitor 98.00% Phase 3
HY-P99540 Tuvonralimab Inhibitor 99.14% Phase 3
HY-P99166 Vudalimab Inhibitor ≥99.0% Phase 2
HY-P99514 Zalifrelimab Inhibitor 98.28% Phase 2
HY-P99809 Quavonlimab Inhibitor ≥99.0% Phase 2
HY-P99714 Lorigerlimab Inhibitor / Phase 2
HY-P99760 Nurulimab Inhibitor 95.00% Phase 1
HY-P99844 Davoceticept / Phase 1
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03299 CTLA4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03300 Ctla4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03301 Ctla4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99132 Anti-Mouse CTLA-4 Antibody (9D9) ≥98.0% Unkown
HY-108829A Abatacept (powder) Inhibitor 95.00% Unkown
HY-P990041 Firastotug Inhibitor / Unkown
HY-P990048 Muzastotug Inhibitor / Unkown
HY-P990703 Porustobart / Unkown
HY-P99354 Bavunalimab / Unkown
HY-P99943 Erfonrilimab / Unkown
HY-P990080 Sovipostobart Inhibitor / Unkown
HY-P990690 Volrustomig / Unkown
HY-P990722 Danvilostomig / Unkown
HY-P990739 Evalstotug / Unkown
HY-P990775 Vilastobart / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CTLA4 NCBI NCBI:1493
Canis familiaris CTLA4 NCBI NCBI:403696
Mus musculus CTLA4 NCBI NCBI:12477
Rattus norvegicus CTLA4 NCBI NCBI:63835
Macaca mulatta CTLA4 NCBI NCBI:705673