2. Gene
  3. CEL - carboxyl ester lipase Gene

CEL - carboxyl ester lipase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BAL; FAP; BSDL; BSSL; CELL; FAPP; LIPA; CEase; MODY8

Gene ID: 1056 | Gene type: protein coding

About CEL

Summary

The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in Cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with Cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]

CEL Products(1)

mRNA Protein Name
NM_001807.6 NP_001798.3 bile salt-activated lipase precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11834744 GOA
Biological Process GO Annotation Evidence Reference Source
involved in intestinal cholesterol absorption IDA
IDA: Inferred from direct assay
12031288 GOA
involved in pancreatic juice secretion IDA
IDA: Inferred from direct assay
1854805 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bile salt-activated lipase

bucelipase

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R04602 MicroRNA Mimic Negative Control 97.85% Unkown
HY-RI04602 MicroRNA Inhibitor Negative Control 94.09% Unkown
HY-RI04602A MicroRNA Antagomir Negative Control 98.61% Unkown
HY-R04602A MicroRNA Agomir Negative Control 97.72% Unkown
HY-158099 Biotin-Cel / Unkown
HY-162407 I-As-1 Inhibitor / Unkown
HY-N0278 Anemonin Inhibitor / Unkown
HY-RS02454 CEL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CEL NCBI
Macaca fascicularis CEL NCBI
Canis lupus familiaris CEL NCBI
Mus musculus CEL NCBI
Susscrofa domestica CEL NCBI
Rattus norvegicus CEL NCBI
Macaca mulatta CEL NCBI