DPYSL4 - dihydropyrimidinase like 4 Gene

Homo sapiens

Also known as CRMP3; DRP-4; ULIP4

Gene ID: 10570 | Gene type: protein coding

About DPYSL4

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:132,186,948-132,205,759 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 5 paralogues. Biased expression in brain (RPKM 6.6), heart (RPKM 2.6) and 6 other tissues.

Summary

Enables filamin binding activity. Predicted to be involved in nervous system development. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

DPYSL4 Products(1)

mRNA	Protein	Name
NM_006426.3	NP_006417.2	dihydropyrimidinase-related protein 4

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables filamin binding	IPI IPI: Inferred from physical interaction	25358863	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	21900206	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPYSL4 Protein Structure

Amidohydro_1

0
100
200
300
400
500
572 a.a.

Protein Preferred Names

Protein Names

dihydropyrimidinase-related protein 4

CRMP-3

DPYSL4 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	DPYSL4	O14531	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	DPYSL4	O14531	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	DPYSL4	O14531	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	DPYSL4	O14531	DPYSL2	Homo sapiens	Q16555	Anti Tag CoIP	33961781
Intra	DPYSL4	O14531	DPYSL2	Homo sapiens	Q16555	Y2H	21900206
Intra	DPYSL4	O14531	TRIP13	Homo sapiens	Q15645	Y2H Prey Pooling	25416956
Intra	DPYSL4	O14531	TRIP13	Homo sapiens	Q15645	Validated Y2H	25416956
Intra	DPYSL4	O14531	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	DPYSL4	O14531	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	DPYSL4	O14531	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	DPYSL4	O14531	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	DPYSL4	O14531	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	DPYSL4	O14531	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	DPYSL4	O14531	RBPMS	Homo sapiens	Q93062	Y2H Prey Pooling	25416956
Intra	DPYSL4	O14531	RBPMS	Homo sapiens	Q93062	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

DPYSL4 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82818	CRMP3 Antibody (YA2563)	WB	Rat

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03983	DPYSL4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	DPYSL4	VGNC	VGNC:61617
Rattus norvegicus	DPYSL4	RGD	RGD:2409
Bos taurus	DPYSL4	VGNC	VGNC:28197
Macaca mulatta	DPYSL4	VGNC	VGNC:71986
Canis familiaris	DPYSL4	VGNC	VGNC:49877
Mus musculus	DPYSL4	MGD	MGI:1349764

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