ATE1 - arginyltransferase 1 Gene

Homo sapiens

Gene ID: 11101 | Gene type: protein coding

About ATE1

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:121,740,424-121,928,463 (from NCBI)

This gene has 73 transcripts (splice variants) and 206 orthologues. Ubiquitous expression in thyroid (RPKM 8.9), testis (RPKM 7.9) and 25 other tissues.

Summary

This gene encodes an arginyltransferase, an Enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

ATE1 Products(5)

mRNA	Protein	Name
NM_001001976.3	NP_001001976.1	arginyl-tRNA--protein transferase 1 isoform 1
NM_001288734.2	NP_001275663.1	arginyl-tRNA--protein transferase 1 isoform 3
NM_001288735.2	NP_001275664.1	arginyl-tRNA--protein transferase 1 isoform 4
NM_001288736.2	NP_001275665.1	arginyl-tRNA--protein transferase 1 isoform 5
NM_007041.4	NP_008972.2	arginyl-tRNA--protein transferase 1 isoform 2

ATE1 Protein Structure

ATE_N

ATE_C

0
100
200
300
400
518 a.a.

Protein Preferred Names

Protein Names

arginyl-tRNA--protein transferase 1

R-transferase 1

Related Diseases

Diseases

Alias

Johanson-Blizzard Syndrome

JBS	Nasal Alar Hypoplasia, Hypothyroidism, Pancreatic Achylia, And Congenital Deafness
Nasal Alar Hypoplasia, Hypothyroidism, Pancreatic Achylia And Congenital Deafness	Johanson Blizzard Syndrome

Chromosome 10q26 Deletion Syndrome

Distal 10q Deletion Syndrome	Terminal Chromosome 10q26 Deletion Syndrome
Distal Monosomy 10q	Monosomy 10qter
Telomeric Deletion 10q	Distal Deletion 10q
10q26 Deletion Syndrome	10qter Deletion
Telomeric Deletion 10

Beare-Stevenson Cutis Gyrata Syndrome

Cutis Gyrata Syndrome Of Beare And Stevenson	Beare-Stevenson Syndrome
BSTVS	Cutis Gyrata-Acanthosis Nigricans-Craniosynostosis Syndrome
Beare Stevenson Syndrome	Cutis Gyrata - Acanthosis Nigricans - Craniosynostosis
Cutis Gyrata Syndrome Of Beare-Stevenson

Jackson-Weiss Syndrome

JWS	Craniosynostosis, Midfacial Hypoplasia, And Foot Abnormalities
Craniosynostosis-Midfacial Hypoplasia-Foot Abnormalities Syndrome	Craniosynostosis-Midfacial Hypoplasia-Foot Abnormalities

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01126	ATE1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ATE1	MGD	MGI:1333870
Rattus norvegicus	ATE1	RGD	RGD:1309335
Macaca mulatta	ATE1	VGNC	VGNC:70168
Bos taurus	ATE1	VGNC	VGNC:26238
Felis catus	ATE1	VGNC	VGNC:68493
Canis familiaris	ATE1	VGNC	VGNC:38206

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