PRAF2 - PRA1 domain family member 2 Gene

Homo sapiens

Also known as JM4; Yip6a

Gene ID: 11230 | Gene type: protein coding

About PRAF2

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:49,071,161-49,074,002 (from NCBI)

This gene has 3 transcripts (splice variants), 143 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 27.2), testis (RPKM 14.5) and 24 other tissues.

Summary

Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in endosome membrane. Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

PRAF2 Products(1)

mRNA	Protein	Name
NM_007213.3	NP_009144.1	PRA1 family protein 2

Protein Preferred Names

Protein Names

PRA1 family protein 2

Jena-Muenchen 4

PRAF2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PRAF2	O60831	RETREG3	Homo sapiens	Q86VR2	Validated Y2H	32296183
Intra	PRAF2	O60831	RETREG3	Homo sapiens	Q86VR2	Y2H Array	32296183
Intra	PRAF2	O60831	RETREG3	Homo sapiens	Q86VR2	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	HSD17B11	Homo sapiens	Q8NBQ5	Y2H Array	32296183
Intra	PRAF2	O60831	HSD17B11	Homo sapiens	Q8NBQ5	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	HSD17B11	Homo sapiens	Q8NBQ5	Validated Y2H	32296183
Intra	PRAF2	O60831	HIBADH	Homo sapiens	P31937	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	HIBADH	Homo sapiens	P31937	Validated Y2H	32296183
Intra	PRAF2	O60831	HIBADH	Homo sapiens	P31937	Y2H Array	32296183
Intra	PRAF2	O60831	NDRG4	Homo sapiens	Q9ULP0-2	Validated Y2H	32296183
Intra	PRAF2	O60831	ZDHHC15	Homo sapiens	Q96MV8	Validated Y2H	32296183
Intra	PRAF2	O60831	ZDHHC15	Homo sapiens	Q96MV8	Y2H Array	32296183
Intra	PRAF2	O60831	ZDHHC15	Homo sapiens	Q96MV8	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	TLCD4	Homo sapiens	Q96MV1	Validated Y2H	32296183
Intra	PRAF2	O60831	TLCD4	Homo sapiens	Q96MV1	Y2H Array	32296183
Intra	PRAF2	O60831	TLCD4	Homo sapiens	Q96MV1	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	PRAF2	O60831	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	AQP6	Homo sapiens	Q13520	Validated Y2H	32296183
Intra	PRAF2	O60831	GPR152	Homo sapiens	Q8TDT2	Validated Y2H	32296183
Intra	PRAF2	O60831	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	PRAF2	O60831	GJA8	Homo sapiens	P48165	Validated Y2H	32296183
Intra	PRAF2	O60831	GJA8	Homo sapiens	P48165	Y2H Array	32296183
Intra	PRAF2	O60831	GJA8	Homo sapiens	P48165	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	ADGRD1	Homo sapiens	Q6QNK2	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	ADGRD1	Homo sapiens	Q6QNK2	Validated Y2H	32296183
Intra	PRAF2	O60831	ADGRD1	Homo sapiens	Q6QNK2	Y2H Array	32296183
Intra	PRAF2	O60831	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	SLC10A6	Homo sapiens	Q3KNW5	Validated Y2H	32296183
Intra	PRAF2	O60831	SLC10A6	Homo sapiens	Q3KNW5	Y2H Array	32296183
Intra	PRAF2	O60831	MCEMP1	Homo sapiens	Q8IX19	Validated Y2H	32296183
Intra	PRAF2	O60831	MCEMP1	Homo sapiens	Q8IX19	Y2H Array	32296183
Intra	PRAF2	O60831	MCEMP1	Homo sapiens	Q8IX19	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	CLEC10A	Homo sapiens	Q8IUN9	Validated Y2H	32296183
Intra	PRAF2	O60831	CLEC10A	Homo sapiens	Q8IUN9	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	CLEC10A	Homo sapiens	Q8IUN9	Y2H Array	32296183
Intra	PRAF2	O60831	RNF5	Homo sapiens	Q99942	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	RNF5	Homo sapiens	Q99942	Validated Y2H	32296183
Intra	PRAF2	O60831	RNF5	Homo sapiens	Q99942	Y2H Array	32296183
Intra	PRAF2	O60831	ABHD16A	Homo sapiens	O95870	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	ABHD16A	Homo sapiens	O95870	Validated Y2H	32296183
Intra	PRAF2	O60831	ABHD16A	Homo sapiens	O95870	Y2H Array	32296183
Intra	PRAF2	O60831	CFTR	Homo sapiens	P13569	Ub Reconstruction	35156780
Intra	PRAF2	O60831	AGR3	Homo sapiens	Q8TD06	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	AGR3	Homo sapiens	Q8TD06	Validated Y2H	32296183
Intra	PRAF2	O60831	AGR3	Homo sapiens	Q8TD06	Y2H Array	32296183
Intra	PRAF2	O60831	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
Intra	PRAF2	O60831	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
Intra	PRAF2	O60831	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	MIEF1	Homo sapiens	Q9NQG6	Validated Y2H	32296183
Intra	PRAF2	O60831	GJA5	Homo sapiens	P36382	Y2H Array	32296183
Intra	PRAF2	O60831	GJA5	Homo sapiens	P36382	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	GJA5	Homo sapiens	P36382	Validated Y2H	32296183
Intra	PRAF2	O60831	CIAO2A	Homo sapiens	Q9H5X1	Validated Y2H	32296183
Intra	PRAF2	O60831	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	REEP4	Homo sapiens	Q9H6H4	Validated Y2H	32296183
Intra	PRAF2	O60831	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183
Intra	PRAF2	O60831	CD79A	Homo sapiens	P11912	Y2H Array	32296183
Intra	PRAF2	O60831	CD79A	Homo sapiens	P11912	Validated Y2H	32296183
Intra	PRAF2	O60831	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
Intra	PRAF2	O60831	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	PRAF2	O60831	EBAG9	Homo sapiens	O00559	Y2H Prey Pooling	32296183
Intra	PRAF2	O60831	EBAG9	Homo sapiens	O00559	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Neuroblastoma

Nb	Neuroblastoma, Susceptibility To
Neuroblastomas	Central Neuroblastoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11046	PRAF2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRAF2	RGD	RGD:1566287
Mus musculus	PRAF2	MGD	MGI:1859607
Bos taurus	PRAF2	VGNC	VGNC:33283
Felis catus	PRAF2	VGNC	VGNC:64342
Canis familiaris	PRAF2	VGNC	VGNC:44939

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