2. Gene
  3. CMTM3 - CKLF like MARVEL transmembrane domain containing 3 Gene

CMTM3 - CKLF like MARVEL transmembrane domain containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BNAS2; CKLFSF3

Gene ID: 123920 | Gene type: protein coding

About CMTM3

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:66,603,996-66,613,892 (from NCBI)

This gene has 15 transcripts (splice variants), 204 orthologues and 14 paralogues. Broad expression in testis (RPKM 24.7), placenta (RPKM 16.7) and 24 other tissues.

Summary

This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

CMTM3 Products(4)

mRNA Protein Name
NM_001363918.2 NP_001350847.1 CKLF-like MARVEL transmembrane domain-containing protein 3
NM_001363923.2 NP_001350852.1 CKLF-like MARVEL transmembrane domain-containing protein 3
NM_144601.5 NP_653202.1 CKLF-like MARVEL transmembrane domain-containing protein 3
NM_181553.4 NP_853531.1 CKLF-like MARVEL transmembrane domain-containing protein 3
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
28428220 GOA
located in cytosol IDA
IDA: Inferred from direct assay
28428220 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CMTM3 Protein Structure

MARVEL

MARVEL: Membrane-associating domain (58 - 149)

  • 0
  • 100
  • 182 a.a.
Protein Preferred Names Protein Names

CKLF-like MARVEL transmembrane domain-containing protein 3

chemokine-like factor superfamily member 3

CMTM3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CMTM3 Q96MX0 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra
CMTM3 Q96MX0 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 IL10RA Homo sapiens Q13651
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 IL10RA Homo sapiens Q13651
Y2H Array
32296183
Intra
CMTM3 Q96MX0 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra
CMTM3 Q96MX0 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
CMTM3 Q96MX0 IKBIP Homo sapiens Q70UQ0-4
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 IKBIP Homo sapiens Q70UQ0-4
Y2H Array
32296183
Intra
CMTM3 Q96MX0 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
CMTM3 Q96MX0 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 LEUTX Homo sapiens A8MZ59
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 LEUTX Homo sapiens A8MZ59
Y2H Array
32296183
Intra
CMTM3 Q96MX0 GJB1 Homo sapiens P08034
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 GJB1 Homo sapiens P08034
Y2H Array
32296183
Intra
CMTM3 Q96MX0 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
Intra
CMTM3 Q96MX0 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra
CMTM3 Q96MX0 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 STMN4 Homo sapiens Q9H169-2
Y2H Array
32296183
Intra
CMTM3 Q96MX0 STMN4 Homo sapiens Q9H169-2
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 STMN4 Homo sapiens Q9H169-2
Validated Y2H
32296183
Intra
CMTM3 Q96MX0 F13A1 Homo sapiens P00488
Validated Y2H
32814053
Intra
CMTM3 Q96MX0 F13A1 Homo sapiens P00488
Y2H Array
32814053
Intra
CMTM3 Q96MX0 F13A1 Homo sapiens P00488
Y2H Pooling
32814053
Intra
CMTM3 Q96MX0 LRRC59 Homo sapiens Q96AG4
Y2H Array
32296183
Intra
CMTM3 Q96MX0 LRRC59 Homo sapiens Q96AG4
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra
CMTM3 Q96MX0 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra
CMTM3 Q96MX0 APOA5 Homo sapiens Q6Q788
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 APOA5 Homo sapiens Q6Q788
Y2H Array
32296183
Intra
CMTM3 Q96MX0 MRM1 Homo sapiens Q6IN84
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 MRM1 Homo sapiens Q6IN84
Y2H Array
32296183
Intra
CMTM3 Q96MX0 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
CMTM3 Q96MX0 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 MOB1A Homo sapiens Q9H8S9
Y2H Array
25416956
Intra
CMTM3 Q96MX0 MOB1A Homo sapiens Q9H8S9
Y2H Prey Pooling
25416956
Intra
CMTM3 Q96MX0 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Intra
CMTM3 Q96MX0 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
Intra
CMTM3 Q96MX0 SYT2 Homo sapiens Q8N9I0
Y2H Array
32296183
Intra
CMTM3 Q96MX0 SYT2 Homo sapiens Q8N9I0
Y2H Prey Pooling
32296183
Intra
CMTM3 Q96MX0 MOB3C Homo sapiens Q70IA8
Y2H Array
25416956
Intra
CMTM3 Q96MX0 MOB3C Homo sapiens Q70IA8
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02865 CMTM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CMTM3 VGNC VGNC:39381
Mus musculus CMTM3 MGD MGI:2447162
Bos taurus CMTM3 VGNC VGNC:27483
Macaca mulatta CMTM3 VGNC VGNC:71215
Felis catus CMTM3 VGNC VGNC:61000
Rattus norvegicus CMTM3 RGD RGD:1308763