ZG16B - zymogen granule protein 16B Gene

Homo sapiens

Also known as EECP; PAUF; JCLN2; HRPE773; PRO1567

Gene ID: 124220 | Gene type: protein coding

About ZG16B

This gene has 6 transcripts (splice variants), 1 gene allele and 79 orthologues. Restricted expression toward salivary gland (RPKM 15006.7).

Summary

Predicted to enable carbohydrate binding activity. Involved in retina homeostasis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

ZG16B Products(1)

mRNA	Protein	Name
NM_145252.3	NP_660295.3	zymogen granule protein 16 homolog B precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20802527	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cell migration	IDA IDA: Inferred from direct assay	19302292	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in apicolateral plasma membrane	IDA IDA: Inferred from direct assay	19302292	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	19302292	GOA
located in extracellular region	IDA IDA: Inferred from direct assay	19302292	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	36232715	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

zymogen granule protein 16 homolog B

endocrine and exocrine protein

ZG16B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ZG16B	Q96DA0	UBQLN1	Homo sapiens	Q9UMX0-2	Validated Y2H	25416956
Intra	ZG16B	Q96DA0	HAUS8	Homo sapiens	Q9BT25	Validated Y2H	32296183
Intra	ZG16B	Q96DA0	HAUS8	Homo sapiens	Q9BT25	Y2H Array	32296183
Intra	ZG16B	Q96DA0	HAUS8	Homo sapiens	Q9BT25	Y2H Prey Pooling	32296183
Intra	ZG16B	Q96DA0	PNMA1	Homo sapiens	Q8ND90	Y2H Prey Pooling	25416956
Intra	ZG16B	Q96DA0	SGTA	Homo sapiens	O43765	Y2H Array	32296183
Intra	ZG16B	Q96DA0	SGTA	Homo sapiens	O43765	Y2H Prey Pooling	32296183
Intra	ZG16B	Q96DA0	SGTA	Homo sapiens	O43765	Validated Y2H	25416956
Intra	ZG16B	Q96DA0	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	25416956
Intra	ZG16B	Q96DA0	SGTB	Homo sapiens	Q96EQ0	Y2H Array	32296183
Intra	ZG16B	Q96DA0	SGTB	Homo sapiens	Q96EQ0	Y2H Prey Pooling	32296183
Intra	ZG16B	Q96DA0	SGTB	Homo sapiens	Q96EQ0	Validated Y2H	32296183
Intra	ZG16B	Q96DA0	SERTAD3	Homo sapiens	Q9UJW9	Y2H Array	32296183
Intra	ZG16B	Q96DA0	SERTAD3	Homo sapiens	Q9UJW9	Y2H Prey Pooling	32296183
Intra	ZG16B	Q96DA0	SERTAD3	Homo sapiens	Q9UJW9	Validated Y2H	32296183
Intra	ZG16B	Q96DA0	UBAC1	Homo sapiens	Q9BSL1	Y2H Prey Pooling	32296183
Intra	ZG16B	Q96DA0	UBAC1	Homo sapiens	Q9BSL1	Validated Y2H	32296183
Intra	ZG16B	Q96DA0	UBAC1	Homo sapiens	Q9BSL1	Y2H Array	32296183
Intra	ZG16B	Q96DA0	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	ZG16B	Q96DA0	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	ZG16B	Q96DA0	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	ZG16B	Q96DA0	TLR2	Homo sapiens	O60603	Anti Tag CoIP	20802527

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ZG16B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71842	ZG16B Protein, Human (P.pastoris, His)	Q96DA0 (G53-R208)	≥95%
HY-P700451	ZG16B Protein, Human (HEK293, His)	Q96DA0 (G17-R172)	≥95%

Related Diseases

Diseases

Alias

Pancreatic Adenocarcinoma

Adenocarcinoma Of The Pancreas	Adenocarcinoma Of Pancreas
Pancreas Adenocarcinoma	Malignant Exocrine Neoplasm
Primary Pancreatic Adenocarcinoma	Adenocarcinoma Of Islet Cell Of Pancreas
Islet Cell Adenocarcinoma Of Unspecified Site	Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16064	ZG16B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZG16B	RGD	RGD:1562673
Felis catus	ZG16B	VGNC	VGNC:107832
Macaca mulatta	ZG16B	VGNC	VGNC:79851
Canis familiaris	ZG16B	VGNC	VGNC:54092
Others	ZG16B	NCBI

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