2. Gene
  3. Csk - c-src tyrosine kinase Gene

Csk - c-src tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p50CSK

Gene ID: 12988 | Gene type: protein coding

About Csk

Summary

Predicted to enable several functions, including Enzyme binding activity; identical protein binding activity; and non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of cell population proliferation. Located in cell-cell junction. Is expressed in several structures, including Peyer's patch; central nervous system; genitourinary system; gut; and liver and biliary system. Orthologous to human CSK (C-terminal Src kinase). [provided by Alliance of Genome Resources, Apr 2022]

Csk Products(6)

mRNA Protein Name
NM_001304761.2 NP_001291690.1 tyrosine-protein kinase CSK
NM_001411641.1 NP_001398570.1 tyrosine-protein kinase CSK
NM_001411642.1 NP_001398571.1 tyrosine-protein kinase CSK
NM_001411643.1 NP_001398572.1 tyrosine-protein kinase CSK
NM_001411644.1 NP_001398573.1 tyrosine-protein kinase CSK
NM_007783.4 NP_031809.2 tyrosine-protein kinase CSK
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12612075 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
15861137 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15861137 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
15861137 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase CSK

C-Src kinase

protein-tyrosine kinase MPK-2

Recombinant Csk Proteins

Cat. No. Product Name Accession Purity
HY-P72957 CSK Protein, Mouse (sf9, His-GST) P41241 (M1-L450) ≥95%
HY-P75322 CSK Protein, Mouse (sf9) P41241 (M1-L450) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-15196 TAK-285 Inhibitor 99.70% Phase 1
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1180A Pam3CSK4 TFA Agonist 99.66% Unkown
HY-108471 CU-CPT22 Inhibitor ≥99.0% Unkown
HY-112146 MMG-11 Antagonist 99.24% Unkown
HY-130254 CSK-IN-1 Inhibitor 98.61% Unkown
HY-122113 PD173952 99.44% Unkown
HY-148063 DB0614 98.80% Unkown
HY-P1181A Pam2CSK4 TFA Agonist 99.28% Unkown
HY-137345 DB-3-291 Inhibitor 98.03% Unkown
HY-130504 Propargyl-PEG1-acid ≥97.0% Unkown
HY-148061 DB1113 99.28% Unkown
HY-112146A MMG-11 quarterhydrate Antagonist 99.09% Unkown
HY-P1180 Pam3CSK4 Agonist / Unkown
HY-118105 RK-20448 Inhibitor 99.38% Unkown
HY-P10527 CSK substrate / Unkown
HY-P1180B Pam3CSK4 trihydrochloride / Unkown
HY-P1181 Pam2CSK4 Agonist / Unkown
HY-P1405 Pam3CSK4-Biotin Agonist / Unkown
HY-RS03238 CSK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W114420 3-Methyl-L-tyrosine / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Csk NCBI NCBI:1445
Macaca fascicularis Csk NCBI NCBI:102131034
Rattus norvegicus Csk NCBI NCBI:315707
Macaca mulatta Csk NCBI NCBI:702868