1. Gene
  2. CST1 - cystatin SN Gene

CST1 - cystatin SN Gene

Homo sapiens
Gene ID: 1469 | Gene type: protein coding

About CST1

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:23,747,562-23,750,935 (from NCBI)

This gene has 2 transcripts (splice variants), 96 orthologues and 11 paralogues. Restricted expression toward salivary gland (RPKM 7300.7).

Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine Protease Inhibitors, while Others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]

CST1 Products(1)

mRNA Protein Name
NM_001898.3 NP_001889.2 cystatin-SN precursor

CST1 Protein Structure

Cystatin

Cystatin: Cystatin domain (32 - 127)

  • 0
  • 100
  • 141 a.a.
Protein Preferred Names Protein Names

cystatin-SN

cystain-SA-I

Recombinant CST1 Proteins

Cat. No. Product Name Accession Purity
HY-P7867 Cystatin SN/CST1 Protein, Human (HEK293, His) P01037 (W21-S141) ≥95%

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