2. Gene
  3. USP54 - ubiquitin specific peptidase 54 Gene

USP54 - ubiquitin specific peptidase 54 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as C10orf29; bA137L10.3; bA137L10.4

Gene ID: 159195 | Gene type: protein coding

About USP54

This gene has 25 transcripts (splice variants), 205 orthologues and 1 paralogue. Broad expression in thyroid (RPKM 13.4), brain (RPKM 8.5) and 22 other tissues.

Summary

Predicted to enable thiol-dependent Deubiquitinase. Predicted to be involved in protein deubiquitination. [provided by Alliance of Genome Resources, Apr 2022]

USP54 Products(21)

mRNA Protein Name
NM_001320437.2 NP_001307366.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 2
NM_001320441.2 NP_001307370.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 3
NM_001350995.2 NP_001337924.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 4
NM_001378208.1 NP_001365137.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001378209.1 NP_001365138.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001378210.1 NP_001365139.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001391941.1 NP_001378870.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 6
NM_001391942.1 NP_001378871.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 4
NM_001391945.1 NP_001378874.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001391946.1 NP_001378875.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001391947.1 NP_001378876.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 7
NM_001391948.1 NP_001378877.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001391949.1 NP_001378878.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 8
NM_001391950.1 NP_001378879.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 7
NM_001391951.1 NP_001378880.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 9
NM_001391952.1 NP_001378881.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 8
NM_001391953.1 NP_001378882.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 1
NM_001391954.1 NP_001378883.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001391955.1 NP_001378884.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 5
NM_001391956.1 NP_001378885.1 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 1
NM_152586.4 NP_689799.3 inactive ubiquitin carboxyl-terminal hydrolase 54 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
36590171 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16713569 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

USP54 Protein Structure

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (39 - 349)

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  • 1684 a.a.
Protein Preferred Names Protein Names

inactive ubiquitin carboxyl-terminal hydrolase 54

inactive ubiquitin-specific peptidase 54

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15565 USP54 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus USP54 RGD RGD:1303206
Canis familiaris USP54 VGNC VGNC:48203
Bos taurus USP54 VGNC VGNC:36736
Macaca mulatta USP54 VGNC VGNC:106116
Felis catus USP54 VGNC VGNC:66896
Mus musculus USP54 MGD MGI:1926037