2. Gene
  3. Il3 - interleukin 3 Gene

Il3 - interleukin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BPA; PSF; HCGF; Il-3; MCGF; Csfmu

Gene ID: 16187 | Gene type: protein coding

About Il3

Chromosome 11: 54,156,129-54,158,103 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 42 orthologues and is associated with 10 phenotypes.

Summary

Enables cytokine activity; growth factor activity; and interleukin-3 receptor binding activity. Acts upstream of or within several processes, including cell surface receptor signaling pathway; monocyte differentiation; and regulation of phosphate metabolic process. Located in extracellular space. Is expressed in skin; stomach; thymus; and vascular system. Human ortholog(s) of this gene implicated in Graves' disease; asthma; and rheumatoid arthritis. Orthologous to human IL3 (interleukin 3). [provided by Alliance of Genome Resources, Apr 2022]

Il3 Products(1)

mRNA Protein Name
NM_010556.4 NP_034686.2 interleukin-3 precursor

Il3 Protein Structure

IL3

IL3: pfam02059 (34 - 137)

  • 0
  • 100
  • 166 a.a.
Protein Preferred Names Protein Names

interleukin-3

P-cell-stimulating factor

hematopoietic growth factor

mast cell growth factor

multipotential colony-stimulating factor

Recombinant Il3 Proteins

Cat. No. Product Name Accession Purity
HY-P7062A IL-3 Protein, Mouse (His) P01586 (D33-C166) ≥95%
HY-P7062 IL-3 Protein, Mouse P01586 (D33-C166) ≥95%
HY-P70685 IL-3 Protein, Mouse (HEK293, His) P01586 (A27-C166) ≥95%
HY-P73207 IL-3 Protein, Mouse (HEK293) P01586 (A27-C166)/NP_034686.2 ≥95%
HY-P78313 IL-3 Protein, Mouse (HEK293, Fc) P01586 (A27-C166) ≥95%
HY-P700205AF Animal-Free IL-3 Protein, Mouse (His) P01586 (D33-C166) ≥95%

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1402 Hydrocortisone hemisuccinate Inhibitor 99.83% Unkown
HY-B1402B Hydrocortisone hemisuccinate sodium Inhibitor 99.66% Unkown
HY-B1402A Hydrocortisone hemisuccinate hydrate Inhibitor / Unkown
HY-B1402R Hydrocortisone hemisuccinate (Standard) / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99536 Tagraxofusp Inhibitor / Unkown
Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99395 Talacotuzumab Inhibitor 95.00% Phase 3
HY-P99234 Pivekimab Inhibitor ≥95.0% Phase 1
Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112378 D-65476 Inhibitor / Unkown
HY-121874 EP009 Inhibitor / Unkown
HY-155951 JAK3-IN-14 Inhibitor 99.32% Unkown
HY-P1111 Lyn peptide inhibitor Inhibitor / Unkown
HY-P1111A Lyn peptide inhibitor TFA Inhibitor / Unkown
HY-RS06751 IL3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06752 Il3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06753 Il3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06764 IL3RA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-14271 Acreozast / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il3 NCBI NCBI:3562
Canis familiaris Il3 NCBI NCBI:481497
Macaca fascicularis Il3 NCBI NCBI:102118362
Rattus norvegicus Il3 NCBI NCBI:24495
Macaca mulatta Il3 NCBI NCBI:706946