2. Gene
  3. Pabpc1 - poly(A) binding protein, cytoplasmic 1 Gene

Pabpc1 - poly(A) binding protein, cytoplasmic 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pabp; Pabp1; PABP 1

Gene ID: 171350 | Gene type: protein coding

About Pabpc1

Summary

Enables mRNA binding activity. Predicted to be involved in gene silencing by RNA; positive regulation of viral genome replication; and regulation of mRNA catabolic process. Located in dendrite. Part of messenger ribonucleoprotein complex. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1). [provided by Alliance of Genome Resources, Apr 2022]

Pabpc1 Products(1)

mRNA Protein Name
NM_134353.3 NP_599180.1 polyadenylate-binding protein 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mRNA binding IDA
IDA: Inferred from direct assay
11416190 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23770097 RGD
Cellular Component GO Annotation Evidence Reference Source
located in dendrite IDA
IDA: Inferred from direct assay
20596529 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
20596529 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyadenylate-binding protein 1

PABP-1

poly(A)-binding protein 1

Pabpc1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Pabpc1 Q9EPH8 Irs1 Rattus norvegicus P35570
Anti Bait CoIP
23770097
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09948 PABPC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990727 Alextatug / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pabpc1 NCBI NCBI:26986