1. Gene
  2. Nrf1 - nuclear respiratory factor 1 Gene

Nrf1 - nuclear respiratory factor 1 Gene

Mus musculus

Also known as D6Ertd415e

Gene ID: 18181 | Gene type: protein coding

About Nrf1

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within mitochondrion organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; connective tissue; genitourinary system; otic capsule; and skeleton. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human NRF1 (nuclear respiratory factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Nrf1 Products(25)

mRNA Protein Name
NM_001164226.2 NP_001157698.1 nuclear respiratory factor 1 isoform a
NM_001164227.2 NP_001157699.1 nuclear respiratory factor 1 isoform b
NM_001164228.2 NP_001157700.1 nuclear respiratory factor 1 isoform c
NM_001164229.2 NP_001157701.1 nuclear respiratory factor 1 isoform d
NM_001164230.2 NP_001157702.1 nuclear respiratory factor 1 isoform e
NM_001361692.2 NP_001348621.1 nuclear respiratory factor 1 isoform b
NM_001361693.2 NP_001348622.1 nuclear respiratory factor 1 isoform f
NM_001361694.2 NP_001348623.1 nuclear respiratory factor 1 isoform a
NM_001361695.2 NP_001348624.1 nuclear respiratory factor 1 isoform a
NM_001410221.1 NP_001397150.1 nuclear respiratory factor 1 isoform g
NM_001410222.1 NP_001397151.1 nuclear respiratory factor 1 isoform g
NM_001410223.1 NP_001397152.1 nuclear respiratory factor 1 isoform b
NM_001410224.1 NP_001397153.1 nuclear respiratory factor 1 isoform b
NM_001410225.1 NP_001397154.1 nuclear respiratory factor 1 isoform d
NM_001410226.1 NP_001397155.1 nuclear respiratory factor 1 isoform e
NM_001410227.1 NP_001397156.1 nuclear respiratory factor 1 isoform f
NM_001410228.1 NP_001397157.1 nuclear respiratory factor 1 isoform f
NM_001410229.1 NP_001397158.1 nuclear respiratory factor 1 isoform h
NM_001410230.1 NP_001397159.1 nuclear respiratory factor 1 isoform h
NM_001410231.1 NP_001397160.1 nuclear respiratory factor 1 isoform i
NM_001410232.1 NP_001397161.1 nuclear respiratory factor 1 isoform j
NM_001410233.1 NP_001397162.1 nuclear respiratory factor 1 isoform j
NM_001410234.1 NP_001397163.1 nuclear respiratory factor 1 isoform k
NM_001410235.1 NP_001397164.1 nuclear respiratory factor 1 isoform k
NM_010938.5 NP_035068.3 nuclear respiratory factor 1 isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26231763 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within mitochondrion organization IMP
IMP: Inferred from mutant phenotype
11134350 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear respiratory factor 1

NRF-1

alpha palindromic-binding protein

alpha-pal

Nrf1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Nrf1 Q9WU00 Ogt Rattus norvegicus P56558
Pull Down
26231763
Cross: Cross-species interaction Intra: Intraspecies interaction

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrf1 NCBI NCBI:4899