1. Gene
  2. Akt3 - thymoma viral proto-oncogene 3 Gene

Akt3 - thymoma viral proto-oncogene 3 Gene

Mus musculus

Also known as Nmf350; D930002M15Rik

Gene ID: 23797 | Gene type: protein coding

About Akt3

Chromosome 1: 176,847,639-177,085,769 reverse strand.GRCm39:CM000994.3

This gene has 4 transcripts (splice variants), 203 orthologues, 5 paralogues and is associated with 19 phenotypes. Broad expression in CNS E18 (RPKM 12.2), CNS E14 (RPKM 1.5) and 22 other tissues.

Summary

Predicted to enable ATP binding activity; protein kinase C binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of angiogenesis and positive regulation of artery morphogenesis. Acts upstream of or within several processes, including brain morphogenesis; positive regulation of TOR signaling; and positive regulation of cell size. Predicted to be located in plasma membrane. Is expressed in several structures, including genitourinary system; musculature; nervous system; retina; and skin. Human ortholog(s) of this gene implicated in colon cancer; glioblastoma; prostate adenocarcinoma; prostate cancer; and renal cell carcinoma. Orthologous to human Akt3 (Akt serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Akt3 Products(1)

mRNA Protein Name
NM_011785.4 NP_035915.3 RAC-gamma serine/threonine-protein kinase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18160256 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brain morphogenesis IMP
IMP: Inferred from mutant phenotype
15713641 MGI
acts upstream of or within homeostasis of number of cells within a tissue IMP
IMP: Inferred from mutant phenotype
15713641 MGI
acts upstream of or within positive regulation of TOR signaling IMP
IMP: Inferred from mutant phenotype
15713641 MGI
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
28254819 MGI
involved in positive regulation of artery morphogenesis IMP
IMP: Inferred from mutant phenotype
28254819 MGI
acts upstream of or within positive regulation of cell size IMP
IMP: Inferred from mutant phenotype
15713641 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Akt3 Protein Structure

PH_PKB

PH_PKB: cd01241 (3 - 109)

STKc_PKB_gamma

STKc_PKB_gamma: cd05593 (131 - 478)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 479 a.a.
Protein Preferred Names Protein Names

RAC-gamma serine/threonine-protein kinase

PKB gamma

RAC-PK-gamma

protein kinase Akt-3

protein kinase B gamma

Recombinant Akt3 Proteins

Cat. No. Product Name Accession Purity
HY-P72817 AKT3 Protein, Mouse (sf9) Q9WUA6-1 (A106-E479) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Akt3 NCBI NCBI:10000