2. Gene
  3. Il27 - interleukin 27 Gene

Il27 - interleukin 27 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p28; Il30; IL-27; IL27-A; IL-27-A; IL-27p28

Gene ID: 246779 | Gene type: protein coding

About Il27

Summary

Enables interleukin-27 receptor binding activity. Acts upstream of or within positive regulation of defense response to virus by host and regulation of T cell proliferation. Located in extracellular space. Is expressed in decidua; embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and pulmonary tuberculosis. Orthologous to human IL27 (interleukin 27). [provided by Alliance of Genome Resources, Apr 2022]

Il27 Products(1)

mRNA Protein Name
NM_145636.2 NP_663611.1 interleukin-27 subunit alpha precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables interleukin-27 receptor binding IDA
IDA: Inferred from direct assay
12121660 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12121660 MGI
enables signaling receptor binding IDA
IDA: Inferred from direct assay
12121660 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of defense response to virus by host IDA
IDA: Inferred from direct assay
25268627 MGI
acts upstream of or within positive regulation of defense response to virus by host IGI
IGI: Inferred from genetic interaction
25268627 MGI
acts upstream of or within regulation of T cell proliferation IDA
IDA: Inferred from direct assay
12121660 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
12121660 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-27 subunit alpha

IL-27 p28 subunit

IL-27 subunit alpha

interleukin 30

Recombinant Il27 Proteins

Cat. No. Product Name Accession Purity
HY-P72554 IL-27 Protein, Mouse (HEK293, His) O35228 (Y19-P228) & Q8K3I6 (F29-S234) ≥95%
HY-P73200 IL-27 Protein, Mouse (228a.a, HEK293, His) O35228 (Y19-P228) &GSGSGGSGGSGSGKL& Q8K3I6 (F29-S234) ≥95%
HY-P700206AF Animal-Free IL-30/IL-27A Protein, Mouse (His) Q8K3I6 (F29-S234) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990024 Casdozokitug Inhibitor 96.49% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151508 Diamino lipid DAL4 / Unkown
HY-RS06746 IL27 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06747 IL27RA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il27 NCBI NCBI:246778